The average train between Wuppertal and Enschede takes 3h 19m and the fastest train takes 2h 44m. There is a train service every few hours from Wuppertal to Enschede. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Wuppertal and Enschede. The earliest departure is at 5:56 AM in the morning, and the last departure from Wuppertal is at 10:43 PM which arrives into Enschede at 1:27 AM. All services require a transfer, and take on average 3h 19m. The schedules shown below are for the next available departures.

3h 31m • 1 change
3h 31m • 1 change
2h 45m • 1 change
3h 31m • 1 change
3h 31m • 1 change
3h 31m • 1 change
2h 45m • 1 change
3h 31m • 1 change
3h 31m • 1 change
2h 45m • 1 change
3h 31m • 1 change
2h 45m • 1 changeWant to know about travelling from Wuppertal to Enschede? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Wuppertal to Enschede. However, there are services departing from Wuppertal station and arriving at Enschede station via Münster Hauptbahnhof. The journey, including transfers, takes approximately 3h 19m.
Wuppertal to Enschede train services, operated by National Express, depart from Wuppertal Hbf station.
Wuppertal to Enschede train services, operated by National Express, arrive at Enschede station.
Book your Wuppertal to Enschede train tickets online with National Express, Deutsche Bahn Regio (DB Regional) and Deutsche Bahn Intercity (DB IC).
The distance between Wuppertal and Enschede is 108.4 km. The road distance is 170 km.
You can take a train from Wuppertal Hbf to Enschede via Münster Hauptbahnhof in around 3h 9m.