The average train between Wuppertal and Iserlohn takes 57 min and the fastest train takes 47 min. There is a train service every few hours from Wuppertal to Iserlohn. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Wuppertal and Iserlohn. The earliest departure is at 12:19 AM at night, and the last departure from Wuppertal is at 11:46 PM which arrives into Iserlohn at 1:06 AM. All services require a transfer, and take on average 57 min. The schedules shown below are for the next available departures.

55 min • 1 change

1h 6m • 1 change

55 min • 1 change

56 min • 1 change

55 min • 1 change

1h 6m • 1 change

55 min • 1 change

56 min • 1 change

47 min • 1 change

55 min • 1 change

1h 6m • 1 change

55 min • 1 change
Want to know about travelling from Wuppertal to Iserlohn? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Wuppertal to Iserlohn. However, there are services departing from Wuppertal station and arriving at Iserlohn station via Hagen Hbf. The journey, including transfers, takes approximately 57 min.
Wuppertal to Iserlohn train services, operated by Deutsche Bahn Intercity (DB IC), depart from Wuppertal Hbf station.
Wuppertal to Iserlohn train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Iserlohn station.
Book your Wuppertal to Iserlohn train tickets online with Deutsche Bahn Intercity (DB IC), VIAS Rail GmbH and Eurobahn.
The distance between Wuppertal and Iserlohn is 40.8 km. The road distance is 53 km.
You can take a train from Wuppertal Hbf to Iserlohn via Hagen Hbf in around 58 min.