The average train between Wuppertal and Kassel takes 3h 12m and the fastest train takes 2h 40m. There is a train service every few hours from Wuppertal to Kassel. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Wuppertal and Kassel. The earliest departure is at 12:56 AM at night, and the last departure from Wuppertal is at 10:56 PM which arrives into Kassel at 6:52 AM. All services require a transfer, and take on average 3h 12m. The schedules shown below are for the next available departures.

2h 41m • 1 change

3h • 1 change

3h • 1 change

3h • 1 change

2h 41m • 1 change

3h • 1 change

3h • 1 change

3h • 1 change

5h 56m • 1 change

2h 41m • 1 change

3h • 1 change

3h • 1 change
Want to know about travelling from Wuppertal to Kassel? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Wuppertal to Kassel. However, there are services departing from Wuppertal station and arriving at Kassel station via Hamm. The journey, including transfers, takes approximately 3h 12m.
Wuppertal to Kassel train services, operated by National Express, depart from Wuppertal Hbf station.
Wuppertal to Kassel train services, operated by National Express, arrive at Kassel-Wilhelmshoehe station.
Book your Wuppertal to Kassel train tickets online with National Express and Deutsche Bahn Intercity (DB IC).
The distance between Wuppertal and Kassel is 163.7 km. The road distance is 256 km.
You can take a train from Wuppertal Hbf to Kassel-Wilhelmshoehe via Hamm(Westf)Hbf in around 2h 52m.