The average train between Wuppertal and Rome takes 17h 5m and the fastest train takes 12h 51m. The train service runs several times per day from Wuppertal to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Wuppertal and Rome. The earliest departure is at 6:14 AM in the morning, and the last departure from Wuppertal is at 6:14 PM which arrives into Rome at 4:19 PM. All services require a transfer at Basel SBB and take an average of 17h 5m. The schedules shown below are for the next available departures.



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21h 5m • 3 changesWant to know about travelling from Wuppertal to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Wuppertal to Rome. However, there are services departing from Wuppertal Hbf station and arriving at Roma Termini station via Basel SBB station, Lugano station and Milano Centrale station. The journey, including transfers, takes approximately 17h 5m.
Wuppertal to Rome train services, operated by Deutsche Bahn Intercity (DB IC), depart from Wuppertal Hbf station.
Wuppertal to Rome train services, operated by ItaloTreno, arrive at Roma Termini station.
Book your Wuppertal to Rome train tickets online with Omio.
The distance between Wuppertal and Rome is 1117 km. The road distance is 1436 km.
You can take a train from Wuppertal Hbf to Roma Termini via Basel SBB, Lugano, and Milano Centrale in around 13h 47m.