The average train between Wuppertal and Rome takes 15h 5m and the fastest train takes 12h 55m. There is at least one train per day from Wuppertal to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run once daily between Wuppertal and Rome. The earliest departure is at 6:02 AM in the morning, and the last departure from Wuppertal is at 8:14 PM which arrives into Rome at 1:24 PM. All services require a transfer at Basel SBB and take an average of 15h 5m. The schedules shown below are for the next available departures.



13h 17m • 3 changes


12h 55m • 3 changes


13h 10m • 3 changesArrives next day



21h 9m • 3 changesWant to know about travelling from Wuppertal to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Wuppertal to Rome. However, there are services departing from Wuppertal station and arriving at Rome station via Basel SBB. The journey, including transfers, takes approximately 15h 5m.
Wuppertal to Rome train services, operated by Deutsche Bahn Intercity (DB IC), depart from Wuppertal Hbf station.
Wuppertal to Rome train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Roma Termini station.
Book your Wuppertal to Rome train tickets online with Deutsche Bahn Intercity (DB IC), Swiss Federal Railways (SBB CFF FFS) and ItaloTreno.
The distance between Wuppertal and Rome is 1,117 km. The road distance is 1,448 km.
You can take a train from Wuppertal Hbf to Roma Termini via Basel SBB, Lugano, and Milano Centrale in around 14h 1m.