The average train between Zurich and Mendrisio takes 2h 20m and the fastest train takes 2h 13m. There is an hourly train service from Zurich to Mendrisio. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Zurich and Mendrisio. The earliest departure is at 6:33 AM in the morning, and the last departure from Zurich is at 9:05 PM which arrives into Mendrisio at 11:27 PM. All services require a transfer, and take on average 2h 20m. The schedules shown below are for the next available departures.

2h 24m • 1 change

2h 13m • 1 change

2h 24m • 1 change

2h 24m • 1 change

2h 24m • 1 change

2h 13m • 1 change

2h 24m • 1 change

2h 24m • 1 change

2h 24m • 1 change

2h 13m • 1 change

2h 24m • 1 change

2h 24m • 1 change
Want to know about travelling from Zurich to Mendrisio? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Zurich to Mendrisio. However, there are services departing from Zurich station and arriving at Mendrisio station via Lugano. The journey, including transfers, takes approximately 2h 20m.
Zurich to Mendrisio train services, operated by Swiss Federal Railways (SBB CFF FFS), depart from Zürich HB station.
Zurich to Mendrisio train services, operated by Swiss Federal Railways (SBB CFF FFS), arrive at Lugano station.
Book your Zurich to Mendrisio train tickets online with Swiss Federal Railways (SBB CFF FFS).
The distance between Zurich and Mendrisio is 169.6 km. The road distance is 195 km.
Swiss Federal Railways (SBB CFF FFS) operates a train from Zürich HB to Lugano hourly. Tickets cost CHF 60–190 and the journey takes 1h 55m.