The train between Zurich and Sesto San Giovanni takes 3h 34m. There is a train service every few hours from Zurich to Sesto San Giovanni. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Zurich and Sesto San Giovanni. The earliest departure is at 6:33 AM in the morning, and the last departure from Zurich is at 7:33 PM which arrives into Sesto San Giovanni at 11:07 PM. All services require a transfer, and take on average 3h 34m. The schedules shown below are for the next available departures.

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Want to know about travelling from Zurich to Sesto San Giovanni? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Zurich to Sesto San Giovanni. However, there are services departing from Zurich station and arriving at Sesto San Giovanni station via Como S. Giovanni. The journey, including transfers, takes approximately 3h 34m.
Zurich to Sesto San Giovanni train services, operated by Swiss Federal Railways (SBB CFF FFS), depart from Zürich HB station.
Zurich to Sesto San Giovanni train services, operated by Swiss Federal Railways (SBB CFF FFS), arrive at Sesto S.Giovanni station.
Book your Zurich to Sesto San Giovanni train tickets online with Swiss Federal Railways (SBB CFF FFS) and Trenord.
The distance between Zurich and Sesto San Giovanni is 210.3 km. The road distance is 246 km.
You can take a train from Zürich HB to Sesto S.Giovanni via Como S.Giovanni in around 3h 42m.