There are 8 ways to get from 125th Street to Buffalo by plane, train (Amtrak), bus, car, subway, train, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Laguardia Airport to Buffalo Niagara International Airport
best- Fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF)plane LGA - BUF
4h 11m$108–785Bus
cheapest- Take the bus from New York to Buffalobus Adt N816-D / ...
9h 28m$63–283Train
- Take the train from Yonkers Amtrak Station to Buffalotrain Empire Service / ...
9h 22m$117–291Drive 361.8 mi
- Drive from 125th Street to Buffalocar 361.8 mi
7h 16m$66–96Fly John F. Kennedy International Airport to Buffalo Niagara International Airport
- Fly from John F. Kennedy International Airport (JFK) to Buffalo Niagara International Airport (BUF)plane JFK - BUF
4h 30m$87–509Line 6 subway, train to Newark Liberty International Airport, fly to Buffalo Niagara International Airport
- Take the subway from 125th Street to 33 Stsubway
- Take the train from New York Penn Station to Newark Airport Railroad Stationtrain
- Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane EWR - BUF
4h 57m$110–610Fly Laguardia Airport to Rochester, bus
- Fly from Laguardia Airport (LGA) to Rochester (ROC)plane LGA - ROC
- Take the bus from Rochester Bus Stop to Buffalobus
5h 30m$162–999Bus via New York Midtown (Flixbus)
- Take the bus from New York Midtown to Buffalobus FlixBus 2686 / ...
10h 44m$73–117
125th Street to Buffalo by train
Comparing Your Travel Options
The cheapest way to get from 125th Street to Buffalo is to drive which costs $65 - $100 and takes 7h 16m.
The fastest way to get from 125th Street to Buffalo is to fly which takes 4h 11m and costs $100 - $800.
No, there is no direct bus from 125th Street to Buffalo. However, there are services departing from New York and arriving at Buffalo via . The journey, including transfers, takes approximately 9h 28m.
No, there is no direct train from 125th Street to Buffalo. However, there are services departing from 125th Street - Harlem and arriving at Buffalo via Yonkers Amtrak Station. The journey, including transfers, takes approximately 9h 22m.
The distance between 125th Street and Buffalo is 310 miles. The road distance is 364 miles.
The best way to get from 125th Street to Buffalo without a car is to train which takes 9h 22m and costs $110 - $300.
It takes approximately 4h 11m to get from 125th Street to Buffalo, including transfers.
125th Street to Buffalo bus services, operated by Trailways, depart from New York station.
125th Street to Buffalo train services, operated by Amtrak, depart from Yonkers Amtrak Station.
The best way to get from 125th Street to Buffalo is to fly which takes 4h 11m and costs $100 - $800. Alternatively, you can train, which costs $110 - $300 and takes 9h 22m, you could also bus, which costs $60 - $290 and takes 9h 28m.
What companies run services between 125th Street, NY, USA and Buffalo, NY, USA?
American Airlines and Delta fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF) every 4 hours. Alternatively, Amtrak operates a train from Yonkers Amtrak Station to Buffalo twice daily. Tickets cost $230–360 and the journey takes 7h 58m. VIA Rail also services this route once daily.
- Website
- delta.com
Flights from Laguardia Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $100–750
Flights from John F. Kennedy International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 43m
- When
- Every day
- Estimated price
- $65–460
Flights from Laguardia Airport to Rochester
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $130–950
- Website
- united.com
Flights from Newark Liberty International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $80–550
Flights from Newark Liberty International Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 3h 50m
- When
- Every day
- Estimated price
- $100–650
- Website
- jetblue.com
Flights from John F. Kennedy International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $65–460
- Website
- aa.com
Flights from Laguardia Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $100–750
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Yonkers Amtrak Station to Buffalo
- Ave. Duration
- 7h 58m
- Frequency
- Twice daily
- Estimated price
- $230–360
- Website
- Amtrak
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from Yonkers Amtrak Station to Buffalo
- Ave. Duration
- 7h 56m
- Frequency
- Once daily
- Estimated price
- $110–280
- Website
- VIA Rail
- Escape
- $110–250
- Business
- $150–270
- Business Plus
- $160–280
- Economy
- $120–260
- Economy Plus
- $140–270
- Phone
- 877-690-5116
- Website
- MTA Homepage
Subway from 125th Street to 33 St
- Ave. Duration
- 19 min
- Frequency
- Every 5 minutes
- Estimated price
- $3
- Schedules at
- MTA Schedules
- Website
- MTA Homepage
- Website
- MTA: World Cup 2026
- Adult
- $3
- Phone
- +1 973-275-5555
- Website
- New Jersey Transit
Train from New York Penn Station to Newark Airport Railroad Station
- Ave. Duration
- 24 min
- Frequency
- Every 20 minutes
- Estimated price
- $16–20
- Website
- New Jersey Transit
- Website
- NJ Transit: World Cup 2026
- Adult Airport
- $16–20
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $11–18
- Schedules at
- Flixbus USA
Bus from New York Midtown to Buffalo
- Ave. Duration
- 8h 35m
- Frequency
- Every 4 hours
- Estimated price
- $70–110
- Schedules at
- Flixbus USA
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 20m
- Frequency
- 5 times a day
- Estimated price
- $13–20
- Website
- Greyhound
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Booking & Getting There
125th Street to Buffalo bus services, operated by Trailways, arrive at Buffalo station.
125th Street to Buffalo train services, operated by Amtrak, arrive at Buffalo station.
Yes, the driving distance between 125th Street to Buffalo is 364 miles. It takes approximately 7h 16m to drive from 125th Street to Buffalo.
There are 254+ hotels available in Buffalo.