There are 8 ways to get from Agnone to Florence by bus, train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, train
best- Take the bus from Agnone to Iserniabus
- Take the train from Isernia to Roma Terminitrain Re
- Take the train from Roma Termini to Firenze S.M.N.train Fr
6h 18m€52–103Bus
cheapest- Take the bus from Agnone to Iserniabus
- Take the bus from Isernia to Roma, Autostazione Tiburtinabus
- Take the bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Stationbus 510 / ...
7h 58m€24–61Drive 467.1 km
- Drive from Agnone to Florencecar 467.1 km
4h 55m€76–109Bus, train to Fiumicino International Airport, fly to Florence Peretola Airport
- Take the bus from Agnone to Iserniabus
- Take the train from Isernia to Roma Terminitrain
- Fly from Fiumicino International Airport (FCO) to Florence Peretola Airport (FLR)plane FCO - FLR
7h 22m€89–246Bus, train via Firenze Santa Maria Novella
- Take the bus from Agnone to Iserniabus
- Take the train from Isernia to Roma Terminitrain Re
- Take the train from Roma Termini to Firenze Santa Maria Novellatrain
6h 19m€54–88Bus, train #2
- Take the bus from Agnone to Iserniabus
- Take the train from Isernia to Cassinotrain Re
- Take the bus from Cassino to Florence - Villa Costanzabus
8h 53m€36–54Bus, train to Naples Airport, fly to Florence Peretola Airport
- Take the bus from Agnone to Iserniabus
- Take the train from Isernia to Casertatrain
- Fly from Naples Airport (NAP) to Florence Peretola Airport (FLR)plane NAP - FLR
9h 3m€101–284Bus, train to Fiumicino International Airport, fly to Bologna Guglielmo Marconi Airport, train
- Take the bus from Agnone to Iserniabus
- Take the train from Isernia to Roma Terminitrain
- Fly from Fiumicino International Airport (FCO) to Bologna Guglielmo Marconi Airport (BLQ)plane FCO - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
8h 4m€86–246
Agnone to Florence by bus and train
Comparing Your Travel Options
The cheapest way to get from Agnone to Florence is to bus which costs €24 - €65 and takes 7h 58m.
The fastest way to get from Agnone to Florence is to drive which takes 4h 55m and costs €75 - €110.
No, there is no direct bus from Agnone to Florence station. However, there are services departing from Agnone and arriving at Florence Villa Constanza Bus Station via Isernia and Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 7h 58m.
The distance between Agnone and Florence is 502 km. The road distance is 467.1 km.
The best way to get from Agnone to Florence without a car is to bus and train which takes 6h 18m and costs €50 - €110.
It takes approximately 6h 18m to get from Agnone to Florence, including transfers.
Agnone to Florence bus services, operated by Società Autocooperative Trasporti Italiani S.p.A., depart from Agnone station.
Agnone to Florence bus services, operated by Società Autocooperative Trasporti Italiani S.p.A., arrive at Isernia station.
Yes, the driving distance between Agnone to Florence is 467 km. It takes approximately 4h 55m to drive from Agnone to Florence.
There are 8310+ hotels available in Florence.
What companies run services between Agnone, Molise, Italy and Florence, Italy?
You can take a bus from Agnone to Florence Villa Constanza Bus Station via Isernia and Roma, Autostazione Tiburtina in around 7h 58m.
- Website
- ita-airways.com
Flights from Fiumicino International Airport to Florence Peretola Airport
- Ave. Duration
- 56 min
- When
- Every day
- Estimated price
- €60–150
Flights from Naples Airport to Florence Peretola Airport via Fiumicino International Airport
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- €140–250
Flights from Naples Airport to Florence Peretola Airport via Nice
- Ave. Duration
- 3h 40m
- When
- Monday, Wednesday, and Friday
- Estimated price
- €65–250
Flights from Fiumicino International Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 3m
- When
- Every day
- Estimated price
- €55–140
- Website
- volotea.com
Flights from Fiumicino International Airport to Florence Peretola Airport
- Ave. Duration
- 56 min
- When
- Every day
- Estimated price
- €60–150
Flights from Naples Airport to Florence Peretola Airport via Fiumicino International Airport
- Ave. Duration
- 3h 25m
- When
- Every day
- Estimated price
- €140–250
Flights from Naples Airport to Florence Peretola Airport via Palermo
- Ave. Duration
- 3h 20m
- When
- Tuesday and Thursday
- Estimated price
- €65–270
Flights from Naples Airport to Florence Peretola Airport via Catania
- Ave. Duration
- 3h 40m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €65–270
Flights from Fiumicino International Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 3m
- When
- Every day
- Estimated price
- €55–140
- Website
- aircorsica.com
Flights from Naples Airport to Florence Peretola Airport via Nice
- Ave. Duration
- 3h 40m
- When
- Monday, Wednesday, and Friday
- Estimated price
- €65–250
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Isernia to Roma Termini
- Ave. Duration
- 2h 24m
- Frequency
- Every 3 hours
- Estimated price
- €22–35
- Website
- Trenitalia
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 3h 40m
- Frequency
- Every 3 hours
- Estimated price
- €30–45
- Website
- Trenitalia
Train from Isernia to Roma Termini
- Ave. Duration
- 2h 24m
- Frequency
- Every 3 hours
- Estimated price
- €22–35
- Website
- Trenitalia
Train from Isernia to Roma Termini
- Ave. Duration
- 2h 24m
- Frequency
- Every 3 hours
- Estimated price
- €22–35
- Website
- Trenitalia
Train from Isernia to Cassino
- Ave. Duration
- 46 min
- Frequency
- Every 2 hours
- Estimated price
- €6–9
- Website
- Trenitalia
Train from Isernia to Caserta
- Ave. Duration
- 1h 12m
- Frequency
- Every 3 hours
- Estimated price
- €10–15
- Website
- Trenitalia
Train from Isernia to Roma Termini
- Ave. Duration
- 2h 24m
- Frequency
- Every 3 hours
- Estimated price
- €22–35
- Website
- Trenitalia
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 35m
- Frequency
- 4 times a day
- Estimated price
- €11–15
- Website
- Trenitalia
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 1h 42m
- Frequency
- Every 20 minutes
- Estimated price
- €35–65
- Website
- Trenitalia Frecce
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Every 20 minutes
- Estimated price
- €12–22
- Website
- Trenitalia Frecce
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 3h 45m
- Frequency
- Twice daily
- Estimated price
- €28–55
- Website
- Trenitalia Intercity
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- Twice daily
- Estimated price
- €9–18
- Website
- Trenitalia Intercity
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Roma Termini to Firenze Santa Maria Novella
- Ave. Duration
- 1h 37m
- Frequency
- Every 30 minutes
- Estimated price
- €30–50
- Website
- Italo Treno
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 38 min
- Frequency
- 5 times a day
- Estimated price
- €11–18
- Website
- Italo Treno
- Phone
- 0865.221788
- [email protected]
- Website
- satiautobus.com
Bus from Agnone to Isernia
- Ave. Duration
- 1h 5m
- Frequency
- 4 times a day
- Estimated price
- €2–3
- Schedules at
- satiautobus.com
Bus from Agnone to Isernia
- Ave. Duration
- 1h 5m
- Frequency
- 4 times a day
- Estimated price
- €2–3
- Schedules at
- satiautobus.com
Bus from Agnone to Isernia
- Ave. Duration
- 1h 5m
- Frequency
- 4 times a day
- Estimated price
- €2–3
- Schedules at
- satiautobus.com
Bus from Agnone to Isernia
- Ave. Duration
- 1h 5m
- Frequency
- 4 times a day
- Estimated price
- €2–3
- Schedules at
- satiautobus.com
Bus from Agnone to Isernia
- Ave. Duration
- 1h 5m
- Frequency
- 4 times a day
- Estimated price
- €2–3
- Schedules at
- satiautobus.com
Bus from Agnone to Isernia
- Ave. Duration
- 1h 5m
- Frequency
- 4 times a day
- Estimated price
- €2–3
- Schedules at
- satiautobus.com
Bus from Agnone to Isernia
- Ave. Duration
- 1h 5m
- Frequency
- 4 times a day
- Estimated price
- €2–3
- Schedules at
- satiautobus.com
- Phone
- +39 0874 64744
- [email protected]
- Website
- atm-molise.it
Bus from Isernia to Roma, Autostazione Tiburtina
- Ave. Duration
- 2h 10m
- Frequency
- 3 times a day
- Estimated price
- €8–13
- Schedules at
- atm-molise.it
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Isernia to Roma, Autostazione Tiburtina
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- €15–23
- Website
- Flixbus
Bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Station
- Ave. Duration
- 3h 15m
- Frequency
- Hourly
- Estimated price
- €23–35
- Website
- Flixbus
- Phone
- +39 06 88 93 82 32
- Website
- Itabus S.p.A.
Bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Station
- Ave. Duration
- 3h 15m
- Frequency
- Twice daily
- Estimated price
- €14–25
- Website
- Itabus S.p.A.
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Station
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- €19–35
- Website
- BlaBlaCar Bus
- Phone
- +39 0972 24590
- [email protected]
- Website
- autolineemoretti.it
Bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Station
- Ave. Duration
- 4h 15m
- Frequency
- 3 times a week
- Estimated price
- €19–22
- Schedules at
- autolineemoretti.it
- Phone
- +39 089 233 899
- [email protected]
- Website
- Curcio Viaggi
Bus from Cassino to Florence - Villa Costanza
- Ave. Duration
- 4h 30m
- Frequency
- Once daily
- Estimated price
- €26–40
- Website
- Curcio Viaggi
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
5 incredible day trips from Florence by train
Read the travel guide
Italy Travel Guides
Read the travel guide
Want to know more about Flixbus?
Read the travel guide









































