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How to get fromAgrigento to Sienaby train, plane, train (Trenitalia), car, ferry, or bus

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There are 11 ways to get from Agrigento to Siena by train, plane, train (Trenitalia), car, ferry, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Palermo Airport, fly to Florence Peretola Airport, train

    best
    1. Take the train from Agrigento Centrale to Palermo Aeroportotrain train
    2. Fly from Palermo Airport (PMO) to Florence Peretola Airport (FLR)plane plane PMO - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    7h 47m
    €73–256

  2. Bus to Catania–Fontanarossa Airport, fly to Florence Peretola Airport, train

    cheapest
    1. Take the bus from Agrigento Piazzale Rosselli to Aeroporto Fontanarossabus bus
    2. Fly from Catania–Fontanarossa Airport (CTA) to Florence Peretola Airport (FLR)plane plane CTA - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    7h 58m
    €48–220

  3. Train

    1. Take the train from Agrigento Centrale to Termini Imeresetrain train Re
    2. Take the train from Termini Imerese to Roma Terminitrain train Ic
    3. Take the train from Roma Termini to Firenze S.M.N.train train Fr
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    17h 44m
    €141–267

  4. Drive, ferry

    1. Drive from Agrigento to Palermocar car
    2. Take the ferry from Palermo to Civitavecchiaferry ferry
    3. Drive from Civitavecchia to Sienacar car
    18h 14m
    €94–159

  5. Bus

    1. Take the bus from Agrigento to Sienabus bus N528
    18h 45m
    €100–160

  6. Train to Palermo Airport, fly to Pisa International Airport, train

    1. Take the train from Agrigento Centrale to Palermo Aeroportotrain train
    2. Fly from Palermo Airport (PMO) to Pisa International Airport (PSA)plane plane PMO - PSA
    3. Take the train from Pisa Centrale to Empolitrain train
    4. Take the train from Empoli to Sienatrain train
    7h 35m
    €72–284

  7. Bus to Catania–Fontanarossa Airport, fly to Pisa International Airport, train

    1. Take the bus from Agrigento Piazzale Rosselli to Aeroporto Fontanarossabus bus
    2. Fly from Catania–Fontanarossa Airport (CTA) to Pisa International Airport (PSA)plane plane CTA - PSA
    3. Take the train from Pisa Centrale to Empolitrain train
    4. Take the train from Empoli to Sienatrain train
    7h 51m
    €64–248

  8. Train to Palermo Airport, fly to Bologna Guglielmo Marconi Airport, train

    1. Take the train from Agrigento Centrale to Palermo Aeroportotrain train
    2. Fly from Palermo Airport (PMO) to Bologna Guglielmo Marconi Airport (BLQ)plane plane PMO - BLQ
    3. Take the train from Bologna Centrale to Firenze S.M.N.train train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    8h 35m
    €54–236

  9. Train to Palermo Airport, fly to Perugia Sant'Egidio Airport, bus

    1. Take the train from Agrigento Centrale to Palermo Aeroportotrain train
    2. Fly from Palermo Airport (PMO) to Perugia Sant'Egidio Airport (PEG)plane plane PMO - PEG
    3. Take the bus from Perugia to Sienabus bus
    9h 13m
    €81–296

  10. Train via Chiusi (Trenitalia)

    1. Take the train from Agrigento Centrale to Termini Imeresetrain train Re
    2. Take the train from Termini Imerese to Roma Terminitrain train Ic
    3. Take the train from Roma Termini to Chiusi-Chianciano T.train train
    4. Take the train from Chiusi-Chianciano T. to Sienatrain train Re
    18h 38m
    €128–230

  11. Bus via Florence

    1. Take the bus from Agrigento Piazzale Rosselli to Florence Villa Constanza Bus Stationbus bus
    2. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131R / ...
    22h 34m
    €209–282

Agrigento to Siena by train

Calendar14Weekly Trains
Duration17h 44mAverage Duration
Ticket€141Cheapest Price
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Comparing Your Travel Options

Map of how to get from Agrigento to Siena.ExpandLaunch map view
  • Distance: 911.7 km
  • Duration: 7h 47m

What companies run services between Agrigento, Italy and Siena, Italy?

You can take a train from Agrigento Centrale to Siena via Termini Imerese, Roma Termini, and Firenze S.M.N. in around 17h 44m. Alternatively, FlixBus operates a bus from Agrigento to Siena once daily. Tickets cost €100–160 and the journey takes 18h 45m.

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