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How to get fromAkron to Mayo Clinicby plane, bus (Flixbus, Greyhound), bus, train, or car

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There are 9 ways to get from Akron to Mayo Clinic by plane, bus (Flixbus, Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Akron to Rochester

    best
    1. Fly from Akron (CAK) to Rochester (RST)plane plane CAK - RST
    7h 4m
    $71–405

  2. Bus via Milwaukee

    1. Take the bus from Robert K Pfaff Transit Center - Akron to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    3. Take the bus from Milwaukee to Rochesterbus bus
    17h 18m
    $147–247

  3. Bus, train

    1. Take the bus from Robert K Pfaff Transit Center - Akron to W. Prospect Ave & Superior Avebus bus 61
    2. Take the train from Cleveland Amtrak to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    4. Take the bus from St. Paul to Rochester, MNbus bus
    20h 5m
    $269–541

  4. Drive 701.6 mi

    1. Drive from Akron to Mayo Cliniccar car 701.6 mi
    12h 4m
    $128–185

  5. Bus to Cleveland-Hopkins International Airport, fly to Rochester

    1. Take the bus from Robert K Pfaff Transit Center - Akron to Cleveland Bus Stationbus bus
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Rochester (RST)plane plane CLE - RST
    7h 5m
    $95–514

  6. Bus to Cleveland-Hopkins International Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the bus from Robert K Pfaff Transit Center - Akron to Cleveland Bus Stationbus bus
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Minneapolis–Saint Paul International Airport (MSP)plane plane CLE - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    6h 58m
    $611–1,066

  7. Bus to John Glenn Columbus International Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the bus from Robert K Pfaff Transit Center - Akron to John Glenn Columbus Intnl Airportbus bus
    2. Fly from John Glenn Columbus International Airport (CMH) to Minneapolis–Saint Paul International Airport (MSP)plane plane CMH - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    9h 29m
    $475–1,069

  8. Bus, train via Madison

    1. Take the bus from Robert K Pfaff Transit Center - Akron to W. Prospect Ave & Superior Avebus bus 61
    2. Take the train from Cleveland Amtrak to Chicago Union Stationtrain train
    3. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    4. Take the bus from Madison to Rochesterbus bus
    19h 2m
    $186–361

  9. Bus

    1. Take the bus from Robert K Pfaff Transit Center - Akron to Cleveland, OHbus bus
    2. Take the bus from Cleveland to Chicagobus bus
    3. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    4. Take the bus from Madison to Rochesterbus bus
    19h 33m
    $113–249

Akron (CAK) to Rochester (RST) flights

Calendar41Weekly Planes
Duration5h 40mAverage Duration
Ticket$70Cheapest Price
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Questions & Answers

Map of how to get from Akron to Mayo Clinic.ExpandLaunch map view
  • Distance: 624.3 mi
  • Duration: 7h 4m

What companies run services between Akron, OH, USA and Mayo Clinic, MN, USA?

American Airlines and United Airlines fly from Akron (CAK) to Rochester (RST) every 4 hours. Alternatively, you can take a bus from Robert K Pfaff Transit Center - Akron to Mayo Clinic via Chicago Bus Station, Milwaukee Intermodal Station, Milwaukee, and Rochester in around 17h 18m.

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Train operators
Bus operators

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