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How to get fromAkron to Mayo Clinicby plane, bus, train, car, or bus (Greyhound, Flixbus)

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There are 9 ways to get from Akron to Mayo Clinic by plane, bus, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Akron to Rochester

    best
    1. Fly from Akron (CAK) to Rochester (RST)plane plane CAK - RST
    7h 39m
    $69–415

  2. Bus, train via Madison

    1. Take the bus from Robert K Pfaff Transit Center - Akron to W. Prospect Ave & Superior Avebus bus 61
    2. Take the train from Cleveland Amtrak to Chicago Union Stationtrain train
    3. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    4. Take the bus from Madison to Rochesterbus bus
    18h 42m
    $256–421

  3. Bus, train

    1. Take the bus from Robert K Pfaff Transit Center - Akron to W. Prospect Ave & Superior Avebus bus 61
    2. Take the train from Cleveland Amtrak to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    4. Take the bus from St. Paul to Rochesterbus bus
    20h
    $429–681

  4. Drive  707.6 mi

    1. Drive from Akron to Mayo Cliniccar car 707.6 mi
    11h 46m
    $130–187

  5. Bus to Cleveland-Hopkins International Airport, fly to Rochester

    1. Take the bus from Robert K Pfaff Transit Center - Akron to Cleveland Bus Stationbus bus
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Rochester (RST)plane plane CLE - RST
    7h 48m
    $90–512

  6. Bus to Cleveland-Hopkins International Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the bus from Robert K Pfaff Transit Center - Akron to Cleveland Bus Stationbus bus
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Minneapolis–Saint Paul International Airport (MSP)plane plane CLE - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    7h 23m
    $859–1,062

  7. Bus to John Glenn Columbus International Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the bus from Robert K Pfaff Transit Center - Akron to John Glenn Columbus Intnl Airportbus bus
    2. Fly from John Glenn Columbus International Airport (CMH) to Minneapolis–Saint Paul International Airport (MSP)plane plane CMH - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    9h 46m
    $493–1,067

  8. Bus

    1. Take the bus from Akron to Clevelandbus bus
    2. Take the bus from Cleveland to Chicagobus bus
    3. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    4. Take the bus from Madison to Rochesterbus bus
    19h 8m
    $113–249

  9. Bus via Milwaukee

    1. Take the bus from Robert K Pfaff Transit Center - Akron to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    3. Take the bus from Milwaukee to Rochesterbus bus
    19h 23m
    $142–224

Akron to Mayo Clinic by bus and foot

Calendar7Weekly Services
Duration19h 8mAverage Duration
Ticket$113Cheapest Price
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Comparing Your Travel Options

Map of how to get from Akron to Mayo Clinic.ExpandLaunch map view
  • Distance: 624.4 mi
  • Duration: 7h 39m

What companies run services between Akron, OH, USA and Mayo Clinic, MN, USA?

American Airlines and United Airlines fly from Akron (CAK) to Rochester (RST) 5 times a day. Alternatively, you can take a bus from Akron to Mayo Clinic via Cleveland, Chicago, W Jackson Blvd, after S Clinton St, 250 N. Lake St - Madison UW Campus, Madison, and Rochester in around 19h 8m.

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