There are 7 ways to get from Alpena to Knoxville by plane, bus (Greyhound, Flixbus), car, bus (Greyhound), bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Mcghee Tyson Airport
best- Fly from Alpena County Regional Airport (APN) to Mcghee Tyson Airport (TYS)plane APN - TYS
7h 2m$224–904Fly to Chattanooga Metropolitan Airport, drive
cheapest- Fly from Alpena County Regional Airport (APN) to Chattanooga Metropolitan Airport (CHA)plane APN - CHA
- Drive from Chattanooga Metropolitan Airport (CHA) to Knoxvillecar
6h 1m$122–462Bus via Toledo
- Take the bus from Alpena to Detroit Greyhoundbus
- Take the bus from Detroit Bus Station to Toledo Bus Stopbus
- Take the bus from Toledo Bus Stop to New York Midtownbus
- Take the bus from New York to Knoxvillebus Nyc
35h 31m$328–530Drive 722.5 mi
- Drive from Alpena to Knoxvillecar 722.5 mi
12h 37m$132–191Bus
- Take the bus from Alpena to Detroit Greyhoundbus
- Take the bus from Detroit Bus Station to Port Authority Bus Terminalbus
- Take the bus from New York to Knoxvillebus Nyc
38h 33m$333–540Bus, train via Farragut
- Take the bus from Alpena to Detroit Greyhoundbus
- Take the bus from Detroit Bus Station to Toledo Bus Stopbus
- Take the train from Toledo to Ny Moynihan Train Hall At Penn Stationtrain
- Take the bus from New York to Knoxvillebus Nyc
38h 33m$428–810Bus, train
- Take the bus from Alpena to Detroit Greyhoundbus
- Take the bus from Detroit Bus Station to Toledo Bus Stopbus
- Take the train from Toledo to Ny Moynihan Train Hall At Penn Stationtrain
- Take the bus from New York, NY to Knoxville, TNbus Ny
38h 37m$383–720
Alpena County Regional Airport (APN) to Mcghee Tyson Airport (TYS) flights
Questions & Answers
The cheapest way to get from Alpena to Knoxville is to drive which costs $130 - $190 and takes 12h 37m.
The fastest way to get from Alpena to Knoxville is to fly and drive which takes 6h 1m and costs $120 - $470.
No, there is no direct bus from Alpena to Knoxville. However, there are services departing from Alpena and arriving at Knoxville via Detroit Bus Station, Toledo Bus Stop and New York. The journey, including transfers, takes approximately 35h 31m.
The distance between Alpena and Knoxville is 666 miles. The road distance is 726.7 miles.
The best way to get from Alpena to Knoxville without a car is to bus via Toledo which takes 35h 31m and costs $320 - $550.
It takes approximately 7h 2m to get from Alpena to Knoxville, including transfers.
Alpena to Knoxville bus services, operated by Indian Trails, depart from Alpena station.
The best way to get from Alpena to Knoxville is to fly which takes 7h 2m and costs $220 - $950. Alternatively, you can bus via Toledo, which costs $320 - $550 and takes 35h 31m.
Alpena to Knoxville bus services, operated by Indian Trails, arrive at Detroit Greyhound station.
Yes, the driving distance between Alpena to Knoxville is 727 miles. It takes approximately 12h 37m to drive from Alpena to Knoxville.
What companies run services between Alpena, MI, USA and Knoxville, TN, USA?
Delta and Allegiant Air fly from Alpena County Regional Airport (APN) to Mcghee Tyson Airport (TYS) twice daily. Alternatively, you can take a vehicle from Alpena to Knoxville via Alpena, Detroit Bus Station, Toledo Bus Stop, New York Midtown, 23 St, East Broadway, New York, and Knoxville in around 35h 31m.
- Website
- delta.com
Flights from Alpena County Regional Airport to Mcghee Tyson Airport via Detroit
- Ave. Duration
- 7h 20m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–800
Flights from Alpena County Regional Airport to Mcghee Tyson Airport via Detroit, Atlanta
- Ave. Duration
- 6h 25m
- When
- Every day
- Estimated price
- $180–900
Flights from Alpena County Regional Airport to Chattanooga Metropolitan Airport via Detroit
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $75–400
Flights from Alpena County Regional Airport to Chattanooga Metropolitan Airport via Detroit, Atlanta
- Ave. Duration
- 8h 8m
- When
- Every day
- Estimated price
- $85–440
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Toledo to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 15h 11m
- Frequency
- Once daily
- Estimated price
- $190–430
- Website
- Amtrak
Train from Toledo to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 15h 11m
- Frequency
- Once daily
- Estimated price
- $190–430
- Website
- Amtrak
- Phone
- +1 989-725-5105
- Website
- Indian Trails
Bus from Alpena to Detroit Greyhound
- Ave. Duration
- 6h 40m
- Frequency
- Once daily
- Estimated price
- $40–75
- Website
- Indian Trails
Bus from Alpena to Detroit Greyhound
- Ave. Duration
- 6h 40m
- Frequency
- Once daily
- Estimated price
- $40–75
- Website
- Indian Trails
Bus from Alpena to Detroit Greyhound
- Ave. Duration
- 6h 40m
- Frequency
- Once daily
- Estimated price
- $40–75
- Website
- Indian Trails
Bus from Alpena to Detroit Greyhound
- Ave. Duration
- 6h 40m
- Frequency
- Once daily
- Estimated price
- $40–75
- Website
- Indian Trails
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
There are 323+ hotels available in Knoxville.




