There are 4 ways to get from Altoona to Cleveland Clinic by train (Amtrak), bus (Greyhound), car, bus, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from Altoona Amtrak Station to Pittsburgh Amtrak Stationtrain Pennsylvanian
- Take the train from Pittsburgh Amtrak Station to Cleveland Amtraktrain Floridian
7h 44m$140–219Drive 210.2 mi
cheapest- Drive from Altoona to Cleveland Cliniccar 210.2 mi
4h 24m$36–52Bus
- Take the bus from Altoona Bus Station to Pittsburgh Intermodal Stationbus
- Take the bus from Pittsburgh Intermodal Station to Robert K Pfaff Transit Center - Akronbus
- Take the bus from RKP Transit Center to Euclid Ave & E. 100th St @ Cleveland Clinicbus 61
9h 28m$46–70Bus, fly
- Take the bus from Altoona Bus Station to State College Bus Stationbus
- Fly from Penn State University Park Airport (SCE) to Cleveland-Hopkins International Airport (CLE)plane SCE - CLE
7h 47m$82–469
Altoona to Cleveland Clinic by bus and foot
Comparing Your Travel Options
The cheapest way to get from Altoona to Cleveland Clinic is to drive which costs $35 - $55 and takes 4h 24m.
The fastest way to get from Altoona to Cleveland Clinic is to drive which takes 4h 24m and costs $35 - $55.
No, there is no direct bus from Altoona station to Cleveland Clinic. However, there are services departing from Altoona Bus Station and arriving at Euclid Ave & E. 100th St @ Cleveland Clinic via Pittsburgh Intermodal Station and RKP Transit Center. The journey, including transfers, takes approximately 9h 28m.
No, there is no direct train from Altoona station to Cleveland Clinic station. However, there are services departing from Altoona Amtrak Station and arriving at E 105Th St-Quincy Av Station via Pittsburgh Amtrak Station and Tower City Station Track 13. The journey, including transfers, takes approximately 7h 44m.
The distance between Altoona and Cleveland Clinic is 259 miles. The road distance is 211.4 miles.
The best way to get from Altoona to Cleveland Clinic without a car is to train which takes 7h 44m and costs $140 - $220.
It takes approximately 7h 44m to get from Altoona to Cleveland Clinic, including transfers.
Altoona to Cleveland Clinic bus services, operated by Greyhound USA, depart from Altoona Bus Station.
Altoona to Cleveland Clinic train services, operated by Amtrak, depart from Altoona Amtrak Station.
The best way to get from Altoona to Cleveland Clinic is to train which takes 7h 44m and costs $140 - $220. Alternatively, you can bus, which costs $45 - $70 and takes 9h 28m.
What companies run services between Altoona, PA, USA and Cleveland Clinic, OH, USA?
You can take a train from Altoona Amtrak Station to Cleveland Clinic via Pittsburgh Amtrak Station, Cleveland Amtrak, Tower City Station Track 13, and E 105Th St-Quincy Av Station in around 7h 44m. Alternatively, you can take a bus from Altoona Bus Station to Cleveland Clinic via Pittsburgh Intermodal Station, RKP Transit Center, and Euclid Ave & E. 100th St @ Cleveland Clinic in around 9h 28m.
- Website
- united.com
Flights from Penn State University Park Airport to Cleveland-Hopkins International Airport via Washington Dulles
- Ave. Duration
- 3h 46m
- When
- Every day
- Estimated price
- $70–450
Flights from Penn State University Park Airport to Cleveland-Hopkins International Airport via Chicago O'Hare
- Ave. Duration
- 4h 53m
- When
- Every day
- Estimated price
- $100–550
- Website
- aa.com
Flights from Penn State University Park Airport to Cleveland-Hopkins International Airport via Philadelphia
- Ave. Duration
- 4h 39m
- When
- Every day
- Estimated price
- $80–470
Flights from Penn State University Park Airport to Cleveland-Hopkins International Airport via Charlotte
- Ave. Duration
- 5h 40m
- When
- Every day
- Estimated price
- $100–550
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Altoona Amtrak Station to Pittsburgh Amtrak Station
- Ave. Duration
- 2h 49m
- Frequency
- Once daily
- Estimated price
- $60–100
- Website
- Amtrak
Train from Pittsburgh Amtrak Station to Cleveland Amtrak
- Ave. Duration
- 2h 54m
- Frequency
- Once daily
- Estimated price
- $75–120
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Altoona Bus Station to Pittsburgh Intermodal Station
- Ave. Duration
- 3h 40m
- Frequency
- Once daily
- Estimated price
- $20–30
- Website
- Greyhound
Bus from Pittsburgh Intermodal Station to Robert K Pfaff Transit Center - Akron
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $21–35
- Website
- Greyhound
Bus from Altoona Bus Station to State College Bus Station
- Ave. Duration
- 50 min
- Frequency
- Once daily
- Estimated price
- $7–12
- Website
- Greyhound
- Website
- yourmetrobus.org
Bus from RKP Transit Center to Euclid Ave & E. 100th St @ Cleveland Clinic
- Ave. Duration
- 1h 20m
- Frequency
- 4 times a day
- Estimated price
- $5
- Schedules at
- yourmetrobus.org
Want to know more about travelling around United States
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Booking & Getting There
Altoona to Cleveland Clinic bus services, operated by Greyhound USA, arrive at Pittsburgh Intermodal Station.
Altoona to Cleveland Clinic train services, operated by Amtrak, arrive at Pittsburgh Amtrak Station.
Yes, the driving distance between Altoona to Cleveland Clinic is 211 miles. It takes approximately 4h 24m to drive from Altoona to Cleveland Clinic.
There are 717+ hotels available in Cleveland Clinic.







