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How to get fromAmes to Charlestonby shuttle, plane, bus, train, or car

Find Transport to Charleston

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There are 5 ways to get from Ames to Charleston by shuttle, plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Shuttle, fly to Charleston International Airport

    best
    1. Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IAshuttle bus
    2. Fly from Des Moines (DSM) to Charleston International Airport (CHS)plane plane DSM - CHS
    7h 44m
    $244–942

  2. Drive 1,168.9 mi

    cheapest
    1. Drive from Ames to Charlestoncar car 1,168.9 mi
    21h 13m
    $214–309

  3. Bus, train

    1. Take the bus from Ames to St. Paulbus bus
    2. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain train
    4. Take the train from Petersburg Amtrak Station to Charleston Amtrak Stationtrain train
    42h 6m
    $618–1,230

  4. Shuttle, fly to Hilton Head Airport, drive

    1. Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IAshuttle bus
    2. Fly from Des Moines (DSM) to Hilton Head Airport (HHH)plane plane DSM - HHH
    3. Drive from Hilton Head Airport (HHH) to Charlestoncar car
    9h 4m
    $240–917

  5. Bus, train via New York

    1. Take the bus from Ames to Des Moinesbus bus
    2. Take the bus from Des Moines to Indianapolisbus bus
    3. Take the train from Indianapolis to Ny Moynihan Train Hall At Penn Stationtrain train
    4. Take the train from Ny Moynihan Train Hall At Penn Station to Charleston Amtrak Stationtrain train
    2d 3h

Des Moines (DSM) to Charleston International Airport (CHS) flights

Calendar103Weekly Planes
Duration5h 39mAverage Duration
Ticket$160Cheapest Price
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Questions & Answers

Map of how to get from Ames to Charleston.ExpandLaunch map view
  • Distance: 1,011.8 mi
  • Duration: 7h 44m

What companies run services between Ames, IA, USA and Charleston, SC, USA?

There is no direct connection from Ames to Charleston. However, you can take the shuttle to Des Moines International Airport, IA, walk to Des Moines (DSM) airport, fly to Charleston International Airport (CHS), walk to Charleston International Airport, then take the line 11 bus to Transit Mall. Alternatively, you can take a bus from Ames to Charleston via St. Paul, St. Paul-Minneapolis, Chicago Union Station, Petersburg Amtrak Station, and Charleston Amtrak Station in around 42h 6m.

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