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How to get fromAmes to Charlotteby shuttle, plane, bus (Greyhound, Amtrak, Flixbus), bus, train, car, or bus (Greyhound, Flixbus)

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There are 6 ways to get from Ames to Charlotte by shuttle, plane, bus (Greyhound, Amtrak, Flixbus), bus, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Shuttle, fly

    best
    1. Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IAshuttle bus
    2. Fly from Des Moines (DSM) to Charlotte Douglas International Airport (CLT)plane plane DSM - CLT
    4h 48m
    $275–1,143

  2. Drive 1,039.4 mi

    cheapest
    1. Drive from Ames to Charlottecar car 1,039.4 mi
    18h 12m
    $190–274

  3. Bus via Carbondale

    1. Take the bus from Ames to Des Moinesbus bus
    2. Take the bus from Des Moines to St Louis Bus Stationbus bus
    3. Take the bus from St. Louis to Carbondalebus bus
    4. Take the bus from Carbondale Intermodal Station to Atlanta Bus Stationbus bus
    5. Take the bus from Atlanta Downtown to Charlotte Bus Stationbus bus
    27h 24m
    $202–385

  4. Bus, train

    1. Take the bus from Ames to Des Moinesbus bus
    2. Take the bus from Des Moines to Chicago Bus Stationbus bus
    3. Take the train from Chicago Union Station to Carytrain train
    4. Take the train from Cary to Charlotte Amtrak Stationtrain train
    38h 23m
    $470–937

  5. Bus

    1. Take the bus from Ames to Des Moinesbus bus
    2. Take the bus from Des Moines to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Charlotte Bus Stationbus bus
    27h 40m
    $205–387

  6. Bus, train via Ironville

    1. Take the bus from Ames to Des Moinesbus bus
    2. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    3. Take the train from Indianapolis to Ashland Amtrak Stationtrain train
    4. Take the bus from Ashland to Wythevillebus bus
    5. Take the bus from Wytheville to Charlotte Bus Stationbus bus
    27h 50m
    $206–457

Des Moines (DSM) to Charlotte Douglas International Airport (CLT) flights

Calendar74Weekly Planes
Duration4h 12mAverage Duration
Ticket$189Cheapest Price
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Questions & Answers

Map of how to get from Ames to Charlotte.ExpandLaunch map view
  • Distance: 862.3 mi
  • Duration: 4h 48m

What companies run services between Ames, IA, USA and Charlotte, NC, USA?

You can take a bus from Ames to Charlotte Bus Station via Des Moines, St Louis Bus Station, St. Louis, Carbondale Intermodal Station, Atlanta Bus Station, Garnett Station, Civic Center Station, and Atlanta Downtown in around 27h 24m.

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Bus operators

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