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How to get fromAmes to Gatlinburgby shuttle, plane, taxi, bus, car, or train

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There are 10 ways to get from Ames to Gatlinburg by shuttle, plane, taxi, bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Shuttle to Des Moines, fly to Mcghee Tyson Airport, taxi

    best
    1. Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IAshuttle bus
    2. Fly from Des Moines (DSM) to Mcghee Tyson Airport (TYS)plane plane DSM - TYS
    3. Take the taxi from Mcghee Tyson Airport (TYS) to Gatlinburgtaxi taxi
    7h 10m
    $482–1,600

  2. Drive 856.8 mi

    cheapest
    1. Drive from Ames to Gatlinburgcar car 856.8 mi
    15h 22m
    $157–226

  3. Bus, drive

    1. Take the bus from Ames to Des Moinesbus bus
    2. Take the bus from Des Moines to Indianapolisbus bus
    3. Take the bus from Indianapolis to Columbusbus bus
    4. Take the bus from Columbus to Winston Salem(Trans Center)bus bus
    5. Take the bus from Winston Salem(Trans Center) to Asheville, NCbus bus
    6. Drive from Asheville, NC to Gatlinburgcar car
    32h 16m

  4. Bus, train, drive

    1. Take the bus from Ames to Des Moinesbus bus
    2. Take the bus from Des Moines to Indianapolisbus bus
    3. Take the train from Indianapolis to Charlottesvilletrain train
    4. Take the train from Charlottesville to Greensborotrain train
    5. Take the bus from Greensboro Bus Stop to Asheville, NCbus bus
    6. Drive from Asheville, NC to Gatlinburgcar car
    38h 21m

  5. Shuttle to Des Moines, fly to Asheville Regional Airport, drive

    1. Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IAshuttle bus
    2. Fly from Des Moines (DSM) to Asheville Regional Airport (AVL)plane plane DSM - AVL
    3. Drive from Asheville-Airport-AVL to Gatlinburgcar car
    7h 42m
    $227–863

  6. Shuttle to Des Moines, fly to Nashville, drive

    1. Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IAshuttle bus
    2. Fly from Des Moines (DSM) to Nashville (BNA)plane plane DSM - BNA
    3. Drive from Nashville-Airport-BNA to Gatlinburgcar car
    7h 5m
    $227–845

  7. Bus to Minneapolis–Saint Paul International Airport, fly to Mcghee Tyson Airport, taxi

    1. Take the bus from Ames to MSP Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Mcghee Tyson Airport (TYS)plane plane MSP - TYS
    3. Take the taxi from Mcghee Tyson Airport (TYS) to Gatlinburgtaxi taxi
    8h 15m
    $397–1,189

  8. Bus, drive via Chicago

    1. Take the bus from Ames to Des Moinesbus bus
    2. Take the bus from Des Moines to Chicago Bus Stationbus bus
    3. Take the bus from Chicago to N Wilson Rd & Ferrell Pl - Columbusbus bus
    4. Take the bus from Columbus to Charlottebus bus
    5. Take the bus from Charlotte Bus Station to Asheville, NCbus bus
    6. Drive from New Leicester Hwy at Walgreens to Gatlinburgcar car
    35h 31m

  9. Bus, train, drive via Chicago

    1. Take the bus from Ames to Des Moinesbus bus
    2. Take the bus from Des Moines to Chicago Bus Stationbus bus
    3. Take the train from Chicago Union Station to Carytrain train
    4. Take the train from Cary to Greensborotrain train
    5. Take the bus from Greensboro Bus Stop to Asheville, NCbus bus
    6. Drive from Asheville, NC to Gatlinburgcar car
    42h 59m
    $484–1,003

  10. Bus, train, drive via Saint Paul

    1. Take the bus from Ames to St. Paulbus bus
    2. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Raleigh Union Stationtrain train
    4. Take the train from Raleigh Union Station to Greensborotrain train
    5. Take the bus from Greensboro Bus Stop to Asheville, NCbus bus
    6. Drive from Asheville, NC to Gatlinburgcar car
    46h 14m
    $595–1,181

Des Moines (DSM) to Mcghee Tyson Airport (TYS) flights

Calendar83Weekly Planes
Duration5h 15mAverage Duration
Ticket$230Cheapest Price
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Questions & Answers

Map of how to get from Ames to Gatlinburg.ExpandLaunch map view
  • Distance: 734 mi
  • Duration: 7h 10m

What companies run services between Ames, IA, USA and Gatlinburg, TN, USA?

There is no direct connection from Ames to Gatlinburg. However, you can take the shuttle to Des Moines International Airport, IA, walk to Des Moines (DSM) airport, fly to Mcghee Tyson Airport (TYS), then take the taxi to Gatlinburg. Alternatively, you can take a bus from Ames to Gatlinburg via Des Moines, Indianapolis, Indianapolis, Columbus, S 3Rd St & E Town St, E Livingston Ave & Macon Aly, Columbus, Winston Salem(Trans Center), and Asheville, NC in around 32h 16m.

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