There are 6 ways to get from Ames to Jefferson City by bus (Greyhound), car, shuttle, plane, bus, train, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Ames to Kansas Citybus Jefferson Lines 803 / ...
- Take the bus from Kansas City Bus Station to Jefferson Citybus Greyhound US0175s
8h 58m$90–132Drive 288.6 mi
cheapest- Drive from Ames to Jefferson Citycar 288.6 mi
5h 43m$53–77Shuttle to Des Moines, fly
- Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IA
- Fly from Des Moines (DSM) to Columbia Regional Airport (COU)plane DSM - COU
6h 43m$257–850Bus, train
- Take the bus from Ames to Kansas Citybus Jefferson Lines 803 / ...
- Take the train from Kansas City to Jefferson City Stationtrain Missouri River Runner / ...
9h 27m$94–176Taxi to Fort Dodge Municipal Airport, fly
- Take the taxi from Ames to Fort Dodge Municipal Airport (FOD)taxi
- Fly from Fort Dodge Municipal Airport (FOD) to Columbia Regional Airport (COU)plane FOD - COU
12h 59m$300–671Bus to Mason City, fly
- Take the bus from Ames to Mason Citybus
- Fly from Mason City (MCW) to Columbia Regional Airport (COU)plane MCW - COU
7h 22m$186–533
Ames to Jefferson City by bus, foot, and train
Comparing Your Travel Options
The cheapest way to get from Ames to Jefferson City is to drive which costs $50 - $80 and takes 5h 43m.
The fastest way to get from Ames to Jefferson City is to drive which takes 5h 43m and costs $50 - $80.
No, there is no direct bus from Ames to Jefferson City. However, there are services departing from Ames and arriving at Jefferson City via Kansas City Bus Station. The journey, including transfers, takes approximately 8h 58m.
The distance between Ames and Jefferson City is 381 miles. The road distance is 290.3 miles.
The best way to get from Ames to Jefferson City without a car is to bus which takes 8h 58m and costs $90 - $140.
It takes approximately 8h 58m to get from Ames to Jefferson City, including transfers.
Ames to Jefferson City bus services, operated by Jefferson Lines, depart from Ames station.
Ames to Jefferson City bus services, operated by Jefferson Lines, arrive at Kansas City station.
Yes, the driving distance between Ames to Jefferson City is 290 miles. It takes approximately 5h 43m to drive from Ames to Jefferson City.
Book your Ames to Jefferson City bus tickets online with Omio.
What companies run services between Ames, IA, USA and Jefferson City, MO, USA?
You can take a bus from Ames to Jefferson City via Kansas City, Kansas City Bus Station, and Jefferson City in around 8h 58m.
- Website
- aa.com
Flights from Des Moines to Columbia Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 4m
- When
- Every day
- Estimated price
- $130–650
Flights from Des Moines to Columbia Regional Airport via Chicago O'Hare
- Ave. Duration
- 5h 50m
- When
- Every day
- Estimated price
- $85–550
Flights from Fort Dodge Municipal Airport to Columbia Regional Airport via Chicago O'Hare, Dallas/Ft.Worth
- Ave. Duration
- 11h 15m
- When
- Every day
- Estimated price
- $120–600
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Kansas City to Jefferson City Station
- Ave. Duration
- 3h 7m
- Frequency
- Twice daily
- Estimated price
- $35–95
- Website
- Amtrak
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Ames to Kansas City
- Ave. Duration
- 4h 40m
- Frequency
- 3 times a day
- Estimated price
- $55–85
- Book at
- Jefferson Lines
- Adult
- $55–85
Bus from Ames to Kansas City
- Ave. Duration
- 4h 40m
- Frequency
- 3 times a day
- Estimated price
- $55–85
- Book at
- Jefferson Lines
- Adult
- $55–85
Bus from Ames to Mason City
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $30–45
- Book at
- Jefferson Lines
- Adult
- $30–45
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Booking & Getting There
There are 19+ hotels available in Jefferson City.







