There are 4 ways to get from Ames to La Crosse by bus, train, car, shuttle, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, train
best- Take the bus from Ames to St. Paulbus Jefferson Lines 802 / ...
- Take the train from St. Paul-Minneapolis to La Crosse Amtrak Stationtrain Empire Builder / ...
7h 42m$128–190Drive 225.6 mi
cheapest- Drive from Ames to La Crossecar 225.6 mi
4h 18m$42–60Shuttle, fly
- Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IA
- Fly from Des Moines (DSM) to La Crosse (LSE)plane DSM - LSE
5h 54m$191–763Bus
- Take the bus from Ames to St. Paulbus Jefferson Lines 802 / ...
- Take the bus from St. Paul to La Crossebus Jefferson Lines 965
8h 15m$98–145
Ames to La Crosse by bus and train
Comparing Your Travel Options
The cheapest way to get from Ames to La Crosse is to drive which costs $40 - $60 and takes 4h 18m.
The fastest way to get from Ames to La Crosse is to drive which takes 4h 18m and costs $40 - $60.
No, there is no direct bus from Ames to La Crosse. However, there are services departing from Ames and arriving at La Crosse via St. Paul. The journey, including transfers, takes approximately 8h 15m.
The distance between Ames and La Crosse is 352 miles. The road distance is 226.9 miles.
The best way to get from Ames to La Crosse without a car is to bus and train which takes 7h 42m and costs $120 - $190.
It takes approximately 7h 42m to get from Ames to La Crosse, including transfers.
Ames to La Crosse bus services, operated by Jefferson Lines, depart from Ames station.
Ames to La Crosse bus services, operated by Jefferson Lines, arrive at St. Paul station.
Yes, the driving distance between Ames to La Crosse is 227 miles. It takes approximately 4h 18m to drive from Ames to La Crosse.
Book your Ames to La Crosse bus tickets online with Omio.
What companies run services between Ames, IA, USA and La Crosse, WI, USA?
You can take a bus from Ames to La Crosse via St. Paul in around 8h 15m.
- Website
- aa.com
Flights from Des Moines to La Crosse via Chicago O'Hare
- Ave. Duration
- 4h 59m
- When
- Every day
- Estimated price
- $90–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from St. Paul-Minneapolis to La Crosse Amtrak Station
- Ave. Duration
- 2h 47m
- Frequency
- 3 times a day
- Estimated price
- $70–110
- Website
- Amtrak
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Ames to St. Paul
- Ave. Duration
- 3h 55m
- Frequency
- Twice daily
- Estimated price
- $55–80
- Book at
- Jefferson Lines
- Adult
- $55–80
Bus from Ames to St. Paul
- Ave. Duration
- 3h 55m
- Frequency
- Twice daily
- Estimated price
- $55–80
- Book at
- Jefferson Lines
- Adult
- $55–80
Bus from St. Paul to La Crosse
- Ave. Duration
- 3h 20m
- Frequency
- Once daily
- Estimated price
- $40–65
- Book at
- Jefferson Lines
- Adult
- $40–65
- Phone
- +1 320.253.2226
- Website
- Executive Express
Shuttle from Ames, IA - Iowa State University to Des Moines International Airport, IA
- Ave. Duration
- 45 min
- Frequency
- On demand
- Estimated price
- $80–190
- Website
- Executive Express
- Schedules at
- Executive Express Coverage Areas for Minnesota and Iowa
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Booking & Getting There
There are 47+ hotels available in La Crosse.