There are 5 ways to get from Ames to Louisville by shuttle, plane, taxi, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Shuttle to Des Moines, fly to Louisville International Airport
best- Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IA
- Fly from Des Moines (DSM) to Louisville International Airport (SDF)plane DSM - SDF
6h 26m$243–1,143Drive 589.6 mi
cheapest- Drive from Ames to Louisvillecar 589.6 mi
10h 18m$108–156Taxi, bus
- Take the taxi from Ames to Des Moinestaxi
- Take the bus from Des Moines to Indianapolis Union Stationbus
- Take the bus from Indianapolis Union Station to Louisville, KYbus
12h 54m$172–253Taxi to Fort Dodge Municipal Airport, fly to Louisville International Airport
- Take the taxi from Ames to Fort Dodge Municipal Airport (FOD)taxi
- Fly from Fort Dodge Municipal Airport (FOD) to Louisville International Airport (SDF)plane FOD - SDF
7h 42m$256–824Shuttle to Des Moines, fly to Blue Grass Airport, drive
- Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IA
- Fly from Des Moines (DSM) to Blue Grass Airport (LEX)plane DSM - LEX
- Drive from Lexington-Airport-LEX to Louisvillecar
7h 21m$195–809
Des Moines (DSM) to Louisville International Airport (SDF) flights
Comparing Your Travel Options
The cheapest way to get from Ames to Louisville is to drive which costs $100 - $160 and takes 10h 18m.
The fastest way to get from Ames to Louisville is to shuttle and fly which takes 6h 26m and costs $240 - $1,200.
The distance between Ames and Louisville is 529 miles. The road distance is 593 miles.
The best way to get from Ames to Louisville without a car is to taxi and bus which takes 12h 54m and costs $170 - $260.
It takes approximately 6h 26m to get from Ames to Louisville, including transfers.
Louisville is 1h ahead of Ames. It is currently 5:48 PM in Ames and 6:48 PM in Louisville.
Yes, the driving distance between Ames to Louisville is 593 miles. It takes approximately 10h 18m to drive from Ames to Louisville.
There are 628+ hotels available in Louisville.
What companies run services between Ames, IA, USA and Louisville, KY, USA?
There is no direct connection from Ames to Louisville. However, you can take the shuttle to Des Moines International Airport, IA, walk to Des Moines (DSM) airport, fly to Louisville International Airport (SDF), walk to Louisville International Airport, then take the line 02 bus to 2nd @ York. Alternatively, you can take the taxi to Des Moines, take the bus to Indianapolis Union Station, then take the bus to Louisville, KY.
- Website
- delta.com
Flights from Des Moines to Louisville International Airport via Atlanta
- Ave. Duration
- 5h 4m
- When
- Every day
- Estimated price
- $240–1,200
Flights from Des Moines to Louisville International Airport via Detroit
- Ave. Duration
- 6h 43m
- When
- Every day
- Estimated price
- $200–1,100
Flights from Des Moines to Louisville International Airport via Minneapolis
- Ave. Duration
- 6h 3m
- When
- Every day
- Estimated price
- $200–1,100
Flights from Des Moines to Blue Grass Airport via Atlanta
- Ave. Duration
- 5h 11m
- When
- Every day
- Estimated price
- $130–700
Flights from Des Moines to Blue Grass Airport via Detroit
- Ave. Duration
- 6h 46m
- When
- Every day
- Estimated price
- $120–650
Flights from Des Moines to Blue Grass Airport via Minneapolis
- Ave. Duration
- 6h 54m
- When
- Saturday
- Estimated price
- $120–650
- Website
- aa.com
Flights from Des Moines to Louisville International Airport via Charlotte
- Ave. Duration
- 6h 17m
- When
- Every day
- Estimated price
- $250–1,300
Flights from Des Moines to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 6h 15m
- When
- Every day
- Estimated price
- $160–950
Flights from Des Moines to Blue Grass Airport via Charlotte
- Ave. Duration
- 7h 27m
- When
- Every day
- Estimated price
- $140–700
Flights from Des Moines to Blue Grass Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 34m
- When
- Every day
- Estimated price
- $170–800
Flights from Des Moines to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 8h 33m
- When
- Every day
- Estimated price
- $100–600
Flights from Des Moines to Blue Grass Airport via Philadelphia
- Ave. Duration
- 8h 21m
- When
- Tuesday and Saturday
- Estimated price
- $170–850
- Website
- united.com
Flights from Des Moines to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 4h 32m
- When
- Every day
- Estimated price
- $160–950
Flights from Fort Dodge Municipal Airport to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 6h 38m
- When
- Every day
- Estimated price
- $110–650
Flights from Des Moines to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- $100–600
- Website
- southwest.com
Flights from Des Moines to Louisville International Airport via Chicago Midway
- Ave. Duration
- 3h 51m
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $160–950
Flights from Des Moines to Louisville International Airport via Nashville
- Ave. Duration
- 5h 15m
- When
- Monday, Thursday, and Friday
- Estimated price
- $180–1,000
- Phone
- +1 320.253.2226
- Website
- Executive Express
Shuttle from Ames, IA - Iowa State University to Des Moines International Airport, IA
- Ave. Duration
- 45 min
- Frequency
- On demand
- Estimated price
- $80–190
- Website
- Executive Express
- Schedules at
- Executive Express Coverage Areas for Minnesota and Iowa
Shuttle from Ames, IA - Iowa State University to Des Moines International Airport, IA
- Ave. Duration
- 45 min
- Frequency
- On demand
- Estimated price
- $80–190
- Website
- Executive Express
- Schedules at
- Executive Express Coverage Areas for Minnesota and Iowa
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Des Moines to Indianapolis Union Station
- Ave. Duration
- 9h 25m
- Frequency
- Once daily
- Estimated price
- $75–120
- Website
- Greyhound
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Indianapolis Union Station to Louisville, KY
- Ave. Duration
- 1h 55m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Amtrak
- Adult
- $22–45
- Ave. Duration
- 56 min
- Estimated price
- $70–180
Cyclone Cab
- Phone
- +1 515-233-3324
Cyclone Cab
- Phone
- +1 515-233-3324
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