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How to get fromAmes to Louisvilleby shuttle, plane, bus (Greyhound, Amtrak), car, taxi, or bus

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There are 6 ways to get from Ames to Louisville by shuttle, plane, bus (Greyhound, Amtrak), car, taxi, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Shuttle to Des Moines, fly to Louisville International Airport

    best
    1. Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IAshuttle bus
    2. Fly from Des Moines (DSM) to Louisville International Airport (SDF)plane plane DSM - SDF
    6h 31m
    $223–993

  2. Drive 589.9 mi

    cheapest
    1. Drive from Ames to Louisvillecar car 589.9 mi
    10h 17m
    $108–156

  3. Bus

    1. Take the bus from Ames to Des Moinesbus bus
    2. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    14h 50m
    $112–212

  4. Taxi to Fort Dodge Municipal Airport, fly to Louisville International Airport

    1. Take the taxi from Ames to Fort Dodge Municipal Airport (FOD)taxi taxi
    2. Fly from Fort Dodge Municipal Airport (FOD) to Louisville International Airport (SDF)plane plane FOD - SDF
    7h 12m
    $241–724

  5. Shuttle to Des Moines, fly to Blue Grass Airport, drive

    1. Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IAshuttle bus
    2. Fly from Des Moines (DSM) to Blue Grass Airport (LEX)plane plane DSM - LEX
    3. Drive from Lexington-Airport-LEX to Louisvillecar car
    7h 9m
    $325–1,409

  6. Bus to Minneapolis–Saint Paul International Airport, fly to Louisville International Airport

    1. Take the bus from Ames to MSP Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Louisville International Airport (SDF)plane plane MSP - SDF
    7h 57m
    $168–682

Des Moines (DSM) to Louisville International Airport (SDF) flights

Calendar111Weekly Planes
Duration5h 26mAverage Duration
Ticket$147Cheapest Price
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Questions & Answers

Map of how to get from Ames to Louisville.ExpandLaunch map view
  • Distance: 526.1 mi
  • Duration: 6h 31m

What companies run services between Ames, IA, USA and Louisville, KY, USA?

You can take a bus from Ames to Louisville, KY via Des Moines and Indianapolis Union Station in around 14h 50m.

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