There are 9 ways to get from Amsterdam to Mainz-Drais by train, bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Amsterdam Centraal to Frankfurt(M) Flughafen Fernbftrain Ice / ...
4h 43m€51–114Train #2
cheapest- Take the train from Amsterdam Centraal to Mainz Hbftrain Nightjet
5h 52m€45–100Bus
- Take the bus from Amsterdam Centraal Station to Essen Hbfbus Ivano-Frankivsk
- Take the bus from Essen central train station to Wiesbaden central train stationbus FlixBus 027
8h 54m€46–63Drive 422 km
- Drive from Amsterdam to Mainz-Draiscar 422 km
4h 12m€78–113Fly Amsterdam Airport Schiphol to Frankfurt, line 54 bus
- Fly from Amsterdam Airport Schiphol (AMS) to Frankfurt (FRA)plane AMS - FRA
- Take the bus from Mainz, Hauptbahnhof to Drais, Heßlerwegbus
4h 25mTrain via Cologne
- Take the train from Amsterdam Centraal to Koeln Hbftrain Ice
- Take the train from Köln Hbf to Mainz, Hauptbahnhoftrain 55 / ...
5h 28m€58–121Train to Düsseldorf International Airport, fly to Frankfurt
- Take the train from Amsterdam Centraal to Duesseldorf Hbftrain
- Fly from Düsseldorf International Airport (DUS) to Frankfurt (FRA)plane DUS - FRA
5h 32m€124–226Fly Amsterdam Airport Schiphol to Düsseldorf International Airport, train
- Fly from Amsterdam Airport Schiphol (AMS) to Düsseldorf International Airport (DUS)plane AMS - DUS
- Take the train from Duesseldorf Hbf to Frankfurt(M) Flughafen Fernbftrain
5h 7m€159–421Fly Amsterdam Airport Schiphol to Stuttgart Airport, train
- Fly from Amsterdam Airport Schiphol (AMS) to Stuttgart Airport (STR)plane AMS - STR
- Take the train from Hauptbahnhof to Mannheim, Hauptbahnhoftrain
- Take the train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhoftrain
7h€157–457
Amsterdam to Mainz-Drais by train and bus
Comparing Your Travel Options
The cheapest way to get from Amsterdam to Mainz-Drais is to bus which costs €45 - €65 and takes 8h 54m.
The fastest way to get from Amsterdam to Mainz-Drais is to drive which takes 4h 12m and costs €75 - €120.
No, there is no direct bus from Amsterdam station to Mainz-Drais. However, there are services departing from Amsterdam Centraal Station and arriving at Drais, Ober-Olmer Straße via Essen central train station, Wiesbaden Hauptbahnhof and Mainz, Münsterplatz. The journey, including transfers, takes approximately 8h 54m.
No, there is no direct train from Amsterdam to Mainz-Drais. However, there are services departing from Amsterdam Centraal and arriving at Mainz, Hauptbahnhof via Frankfurt. The journey, including transfers, takes approximately 4h 43m.
The distance between Amsterdam and Mainz-Drais is 461 km. The road distance is 422 km.
The best way to get from Amsterdam to Mainz-Drais without a car is to train which takes 4h 43m and costs €50 - €120.
It takes approximately 4h 43m to get from Amsterdam to Mainz-Drais, including transfers.
Amsterdam to Mainz-Drais bus services, operated by GrandBus, depart from Amsterdam Centraal Station.
Amsterdam to Mainz-Drais train services, operated by Nederlandse Spoorwegen (NS), depart from Amsterdam Centraal station.
The best way to get from Amsterdam to Mainz-Drais is to train which takes 4h 43m and costs €50 - €120. Alternatively, you can bus, which costs €45 - €65 and takes 8h 54m.
What companies run services between Amsterdam, Netherlands and Mainz-Drais, Germany?
Nederlandse Spoorwegen (NS) operates a train from Amsterdam Centraal to Frankfurt(M) Flughafen Fernbf hourly. Tickets cost €45–95 and the journey takes 3h 39m. Alternatively, you can take a bus from Amsterdam Centraal Station to Drais, Ober-Olmer Straße via Essen Hbf, Essen central train station, Wiesbaden central train station, Wiesbaden Hauptbahnhof, and Mainz, Münsterplatz in around 8h 54m.
- Website
- klm.com
Flights from Amsterdam Airport Schiphol to Frankfurt
- Ave. Duration
- 1h 7m
- When
- Every day
- Estimated price
- €40–280
Flights from Amsterdam Airport Schiphol to Düsseldorf International Airport
- Ave. Duration
- 48 min
- When
- Every day
- Estimated price
- €35–290
Flights from Amsterdam Airport Schiphol to Stuttgart Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- €55–370
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Amsterdam Centraal to Frankfurt(M) Flughafen Fernbf
- Ave. Duration
- 3h 39m
- Frequency
- Hourly
- Estimated price
- €45–95
- Website
- Nederlandse Spoorwegen (NS)
Train from Amsterdam Centraal to Koeln Hbf
- Ave. Duration
- 2h 38m
- Frequency
- Hourly
- Estimated price
- €28–60
- Website
- Nederlandse Spoorwegen (NS)
Train from Amsterdam Centraal to Mainz Hbf
- Ave. Duration
- 5h 25m
- Frequency
- 6 times a week
- Estimated price
- €45–100
- Website
- Nederlandse Spoorwegen (NS)
Train from Amsterdam Centraal to Duesseldorf Hbf
- Ave. Duration
- 2h 12m
- Frequency
- Hourly
- Estimated price
- €23–50
- Website
- Nederlandse Spoorwegen (NS)
Train from Duesseldorf Hbf to Frankfurt(M) Flughafen Fernbf
- Ave. Duration
- 1h 25m
- Frequency
- Hourly
- Estimated price
- €22–50
- Website
- Nederlandse Spoorwegen (NS)
Train from Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 38 min
- Frequency
- Once daily
- Estimated price
- €11–24
- Website
- Nederlandse Spoorwegen (NS)
- Phone
- +38 098-888-11-08
- [email protected]
- Website
- Grand Bus
Bus from Amsterdam Centraal Station to Essen Hbf
- Ave. Duration
- 2h 26m
- Frequency
- Once daily
- Estimated price
- €26–28
- Website
- Grand Bus
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Booking & Getting There
Amsterdam to Mainz-Drais bus services, operated by GrandBus, arrive at Essen Hbf station.
Amsterdam to Mainz-Drais train services, operated by Nederlandse Spoorwegen (NS), arrive at Frankfurt(M) Flughafen Fernbf station.
Yes, the driving distance between Amsterdam to Mainz-Drais is 422 km. It takes approximately 4h 12m to drive from Amsterdam to Mainz-Drais.
There are 1277+ hotels available in Mainz-Drais.






