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How to get fromAnaheim to Otay Mesaby bus (Greyhound, Flixbus), train, tram, car, or bus (Greyhound)

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There are 4 ways to get from Anaheim to Otay Mesa by bus (Greyhound, Flixbus), train, tram, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Anaheim Regional Transportation Intermodal Center to San Ysidro Bus Terminalbus bus Greyhound US0901 / ...
    3h 31m
    $22–39
  2. Drive  111.2 mi

    cheapest
    1. Drive from Anaheim to Otay Mesacar car 111.2 mi
    2h
    $19–28
  3. Train, tram

    1. Take the train from Fullerton Amtrak Station to San Diego Old Town Transportation Centertrain train Pacific Surfliner
    2. Take the tram from Old Town Station to Iris Avenue Stationtram tram Blue
    3h 43m
    $58–101
  4. Bus, line 929 bus

    1. Take the bus from Anaheim to San Diegobus bus Los Angeles
    2. Take the bus from 12th & Imperial Transit Center to Iris Avenue Transit Centerbus bus 929 / ...
    4h
    $22–37

Anaheim to Otay Mesa by bus

Calendar34Weekly Buses
Duration3h 31mAverage Duration
Ticket$22Cheapest Price
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Comparing Your Travel Options

What companies run services between Anaheim, CA, USA and Otay Mesa, CA, USA?

Greyhound USA operates a bus from Anaheim Regional Transportation Intermodal Center to San Ysidro Bus Terminal 3 times a day. Tickets cost $19–30 and the journey takes 2h 30m. Flixbus USA also services this route twice daily.

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Bus operators

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Need to know: Greyhound

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