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How to get fromAnkeny to Mayo Clinicby bus, car, plane, or shuttle

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There are 5 ways to get from Ankeny to Mayo Clinic by bus, car, plane, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Ames to Albert Leabus bus Jefferson 802 / ...
    2. Take the bus from Albert Lea to Rochesterbus bus Lta 235
    5h 26m

  2. Drive 198.6 mi

    cheapest
    1. Drive from Ankeny to Mayo Cliniccar car 198.6 mi
    3h 19m
    $37–53

  3. Fly to Rochester

    1. Fly from Des Moines (DSM) to Rochester (RST)plane plane DSM - RST
    6h 50m
    $117–659

  4. Shuttle, bus

    1. Take a shuttle bus from Des Moines International Airport, IA to Ames, IA - Iowa State Universityshuttle bus
    2. Take the bus from Ames to Albert Leabus bus
    3. Take the bus from Albert Lea to Rochesterbus bus
    7h 38m

  5. Fly to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Des Moines (DSM) to Minneapolis–Saint Paul International Airport (MSP)plane plane DSM - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    5h 34m
    $174–791

Des Moines (DSM) to Rochester (RST) flights

Calendar62Weekly Planes
Duration5h 38mAverage Duration
Ticket$75Cheapest Price
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Questions & Answers

Map of how to get from Ankeny to Mayo Clinic.ExpandLaunch map view
  • Distance: 210.4 mi
  • Duration: 5h 26m

What companies run services between Ankeny, IA, USA and Mayo Clinic, MN, USA?

You can take a vehicle from Ankeny to Mayo Clinic via Ames, Albert Lea, and Rochester in around 5h 26m. Alternatively, Delta, American Airlines, and United Airlines fly from Des Moines (DSM) to Rochester (RST) every 3 hours.

Airlines
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