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How to get fromAnkeny to Mount Vernonby bus (Greyhound), car, plane, or bus

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There are 8 ways to get from Ankeny to Mount Vernon by bus (Greyhound), car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Greyhound)

    best
    1. Take the bus from Des Moines to St Louis Bus Stationbus bus Greyhound US0153S
    2. Take the bus from St Louis Bus Station to Mount Vernonbus bus Greyhound US0185 / ...
    10h 57m
    $99–176

  2. Drive 415.1 mi

    cheapest
    1. Drive from Ankeny to Mount Vernoncar car 415.1 mi
    8h 8m
    $76–110

  3. Fly Des Moines to Lambert–St. Louis International Airport, bus

    1. Fly from Des Moines (DSM) to Lambert–St. Louis International Airport (STL)plane plane DSM - STL
    2. Take the bus from St Louis Bus Station to Mount Vernonbus bus
    8h 26m
    $205–1,025

  4. Fly Des Moines to Evansville, bus

    1. Fly from Des Moines (DSM) to Evansville (EVV)plane plane DSM - EVV
    2. Take the bus from Evansville Bus Station to Mount Vernonbus bus
    8h 38m
    $184–801

  5. Fly Des Moines to Nashville, bus

    1. Fly from Des Moines (DSM) to Nashville (BNA)plane plane DSM - BNA
    2. Take the bus from Nashville Bus Station to Mount Vernonbus bus
    9h 43m
    $188–872

  6. Fly Des Moines to Chicago Midway International Airport, bus

    1. Fly from Des Moines (DSM) to Chicago Midway International Airport (MDW)plane plane DSM - MDW
    2. Take the bus from Chicago to El Rancherito - Mount Vernonbus bus
    9h
    $184–826

  7. Bus to Omaha, fly to Lambert–St. Louis International Airport, bus

    1. Take the bus from Des Moines to Omaha, NEbus bus
    2. Fly from Omaha (OMA) to Lambert–St. Louis International Airport (STL)plane plane OMA - STL
    3. Take the bus from St Louis Bus Station to Mount Vernonbus bus
    9h 18m
    $664–1,001

  8. Fly Des Moines to Williamson County Regional Airport, bus

    1. Fly from Des Moines (DSM) to Williamson County Regional Airport (MWA)plane plane DSM - MWA
    2. Take the bus from Marathon Gas Station - Marion to El Rancherito - Mount Vernonbus bus
    7h 14m
    $193–889

Des Moines (DSM) to Lambert–St. Louis International Airport (STL) flights

Calendar134Weekly Planes
Duration5h 27mAverage Duration
Ticket$142Cheapest Price
See schedules

Questions & Answers

Map of how to get from Ankeny to Mount Vernon.ExpandLaunch map view
  • Distance: 501.8 mi
  • Duration: 10h 57m

What companies run services between Ankeny, IA, USA and Mount Vernon, IL, USA?

You can take a vehicle from Ankeny to Mount Vernon via Des Moines, St Louis Bus Station, and Mount Vernon in around 10h 57m.

Airlines
Bus operators

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