There are 7 ways to get from Ann Arbor to Des Moines by bus, plane, train, car, bus (Amtrak), or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Detroit, fly
best- Take the bus from Blake Transit Center to DTW McNamara Terminalbus
- Fly from Detroit (DTW) to Des Moines (DSM)plane DTW - DSM
3h 44m$144–736Drive 555 mi
cheapest- Drive from Ann Arbor to Des Moinescar 555 mi
9h 13m$102–147Train, bus
- Take the train from Ann Arbor Amtrak Station to Chicago Union Stationtrain Wolverine
- Take the bus from Chicago to Des Moinesbus Btw 1205 / ...
12h 37m$159–278Train, bus via Galesburg
- Take the train from Ann Arbor Amtrak Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain
- Take the bus from Galesburg to Des Moinesbus
13h 49m$159–333Drive to Capital Region International Airport, fly
- Drive from Ann Arbor to Lansing-Airport-LANcar
- Fly from Capital Region International Airport (LAN) to Des Moines (DSM)plane LAN - DSM
5h 1m$150–739Bus via Chicago
- Take the bus from Ann Arbor Amtrak Station to Chicago Union Stationbus Amtrak Thruway Connecting Service
- Take the bus from Chicago to Des Moinesbus Btw 1205 / ...
12h 58m$165–238Bus
- Take the bus from Ann Arbor to Chicago Bus Stationbus Greyhound US0160
- Take the bus from Chicago to Des Moinesbus Btw 1205 / ...
13h 10m$119–193
Ann Arbor to Des Moines by train, foot, and bus
Questions & Answers
The cheapest way to get from Ann Arbor to Des Moines is to drive which costs $100 - $150 and takes 9h 13m.
The fastest way to get from Ann Arbor to Des Moines is to bus and fly which takes 3h 44m and costs $140 - $750.
No, there is no direct bus from Ann Arbor station to Des Moines. However, there are services departing from Ann Arbor Amtrak Station and arriving at Des Moines via Chicago. The journey, including transfers, takes approximately 12h 58m.
The distance between Ann Arbor and Des Moines is 567 miles. The road distance is 558.2 miles.
The best way to get from Ann Arbor to Des Moines without a car is to train and bus which takes 12h 37m and costs $150 - $280.
It takes approximately 3h 44m to get from Ann Arbor to Des Moines, including transfers.
Ann Arbor to Des Moines bus services, operated by Amtrak, depart from Ann Arbor Amtrak Station.
Ann Arbor to Des Moines bus services, operated by Amtrak, arrive at Chicago Union Station.
Des Moines is 1h behind Ann Arbor. It is currently 4:27 AM in Ann Arbor and 3:27 AM in Des Moines.
Yes, the driving distance between Ann Arbor to Des Moines is 558 miles. It takes approximately 9h 13m to drive from Ann Arbor to Des Moines.
What companies run services between Ann Arbor, MI, USA and Des Moines, IA, USA?
You can take a bus from Ann Arbor Amtrak Station to Des Moines via Chicago Union Station and Chicago in around 12h 58m.
- Website
- delta.com
Flights from Detroit to Des Moines
- Ave. Duration
- 1h 55m
- When
- Every day
- Estimated price
- $120–700
Flights from Detroit to Des Moines via Minneapolis
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $160–800
Flights from Capital Region International Airport to Des Moines via Detroit
- Ave. Duration
- 4h 58m
- When
- Every day
- Estimated price
- $140–800
- Website
- united.com
Flights from Detroit to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 8m
- When
- Every day
- Estimated price
- $120–700
Flights from Capital Region International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 6h 7m
- When
- Every day
- Estimated price
- $120–700
- Website
- aa.com
Flights from Detroit to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 12m
- When
- Every day
- Estimated price
- $120–700
Flights from Capital Region International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 37m
- When
- Every day
- Estimated price
- $120–700
- Website
- southwest.com
Flights from Detroit to Des Moines via Chicago Midway
- Ave. Duration
- 3h 45m
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- $120–700
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Ann Arbor Amtrak Station to Chicago Union Station
- Ave. Duration
- 4h 18m
- Frequency
- 3 times a day
- Estimated price
- $75–160
- Website
- https://www.amtrak.com/home.html
Train from Ann Arbor Amtrak Station to Chicago Union Station
- Ave. Duration
- 4h 18m
- Frequency
- 3 times a day
- Estimated price
- $75–160
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Galesburg Amtrak Station
- Ave. Duration
- 2h 36m
- Frequency
- 4 times a day
- Estimated price
- $50–110
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 517-333-0400
- [email protected]
- Website
- michiganflyer.com
Bus from Blake Transit Center to DTW McNamara Terminal
- Ave. Duration
- 40 min
- Frequency
- Every 4 hours
- Estimated price
- $7–16
- Website
- https://www.michiganflyer.com/
- Child 2-16
- $7–9
- Adult
- $11–16
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Chicago to Des Moines
- Ave. Duration
- 7h 10m
- Frequency
- 3 times a day
- Estimated price
- $80–120
- Book at
- https://www.jeffersonlines.com
- Adult
- $80–120
Bus from Chicago to Des Moines
- Ave. Duration
- 7h 10m
- Frequency
- 3 times a day
- Estimated price
- $80–120
- Book at
- https://www.jeffersonlines.com
- Adult
- $80–120
Bus from Ann Arbor to Chicago Bus Station
- Ave. Duration
- 5h
- Frequency
- 3 times a day
- Estimated price
- $60–90
- Book at
- https://www.jeffersonlines.com
- Adult
- $60–90
Bus from Chicago to Des Moines
- Ave. Duration
- 7h 10m
- Frequency
- 3 times a day
- Estimated price
- $80–120
- Book at
- https://www.jeffersonlines.com
- Adult
- $80–120
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Galesburg to Des Moines
- Ave. Duration
- 4h 55m
- Frequency
- Once daily
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
Bus from Ann Arbor to Chicago Bus Station
- Ave. Duration
- 5h
- Frequency
- 3 times a day
- Estimated price
- $35–75
- Website
- https://www.greyhound.com/
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Ann Arbor Amtrak Station to Chicago Union Station
- Ave. Duration
- 4h 39m
- Frequency
- Once a week
- Estimated price
- $80–120
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Ann Arbor to Chicago Bus Station
- Ave. Duration
- 3h 55m
- Frequency
- 5 times a week
- Estimated price
- $35–65
- Schedules at
- flixbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
Book your Ann Arbor to Des Moines bus tickets online with Omio.
There are 260+ hotels available in Des Moines.









