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How to get fromAnn Arbor to Des Plainesby car, plane, train (Amtrak), bus (Greyhound, Flixbus), bus, train, or bus (Amtrak)

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There are 8 ways to get from Ann Arbor to Des Plaines by car, plane, train (Amtrak), bus (Greyhound, Flixbus), bus, train, or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Capital Region International Airport, fly to Chicago O'Hare International Airport

    best
    1. Drive from Ann Arbor to Lansing-Airport-LANcar car
    2. Fly from Capital Region International Airport (LAN) to Chicago O'Hare International Airport (ORD)plane plane LAN - ORD
    2h 58m
    $54–363
  2. Bus

    cheapest
    1. Take the bus from Ann Arbor to Chicago Bus Stationbus bus Greyhound US0160
    6h 21m
    $45–79
  3. Train (Amtrak)

    1. Take the train from Ann Arbor Amtrak Station to Chicago Union Stationtrain train Wolverine
    5h 28m
    $86–168
  4. Drive 257.8 mi

    1. Drive from Ann Arbor to Des Plainescar car 257.8 mi
    4h 26m
    $47–68
  5. Bus to Detroit, fly to Chicago O'Hare International Airport

    1. Take the bus from Blake Transit Center to DTW McNamara Terminalbus bus
    2. Fly from Detroit (DTW) to Chicago O'Hare International Airport (ORD)plane plane DTW - ORD
    3h 38m
    $158–720
  6. Bus to Detroit, fly to Chicago Midway International Airport, train

    1. Take the bus from Blake Transit Center to DTW McNamara Terminalbus bus
    2. Fly from Detroit (DTW) to Chicago Midway International Airport (MDW)plane plane DTW - MDW
    3. Take the train from Chicago OTC to Des Plainestrain train
    4h 46m
    $143–485
  7. Bus to Detroit, fly to General Mitchell International Airport, bus

    1. Take the bus from Blake Transit Center to DTW McNamara Terminalbus bus
    2. Fly from Detroit (DTW) to General Mitchell International Airport (MKE)plane plane DTW - MKE
    3. Take the bus from Mitchell Airport to O'Hare International Airport - Terminal 2 Departuresbus bus
    5h 20m
    $643–1,109
  8. Bus via Jefferson Park Transit Center (Amtrak)

    1. Take the bus from Ann Arbor Amtrak Station to Chicago Union Stationbus bus Amtrak Thruway Connecting Service
    7h 31m
    $89–124

Ann Arbor to Des Plaines by train, foot, and bus (Amtrak)

Calendar21Weekly Services
Duration5h 28mAverage Duration
Ticket$86Cheapest Price
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Questions & Answers

What companies run services between Ann Arbor, MI, USA and Des Plaines, IL, USA?

Amtrak operates a train from Ann Arbor Amtrak Station to Chicago Union Station 3 times a day. Tickets cost $75–160 and the journey takes 4h 18m. Alternatively, Greyhound-us operates a bus from Ann Arbor to Chicago Bus Station 3 times a day, and the journey takes 5h. Two other operators also service this route.

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