There are 7 ways to get from Ann Arbor to Florida Keys by bus, plane, bus (Greyhound, Flixbus), train, car, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Detroit, fly to Key West International Airport
best- Take the bus from Ann Arbor- Blake Transit Ctr., MI to Detroit Metro Airportbus
- Fly from Detroit (DTW) to Key West International Airport (EYW)plane DTW - EYW
9h 38m$194–661Bus
- Take the bus from Ann Arbor- Blake Transit Ctr., MI to Detroit - Grand Circus Parkbus
- Take the bus from Detroit Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
39h 15m$225–439Bus, train
- Take the bus from Ann Arbor Amtrak Station to Toledobus
- Take the train from Toledo to Miami Amtrak Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
2d 3h$569–1,204Drive 1,469.3 mi
- Drive from Ann Arbor to Florida Keyscar 1,469.3 mi
25h 37m$269–388Bus to Detroit, fly to Miami International Airport, shuttle
- Take the bus from Ann Arbor- Blake Transit Ctr., MI to Detroit Metro Airportbus
- Fly from Detroit (DTW) to Miami International Airport (MIA)plane DTW - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
10h 20m$319–801Bus to Detroit, fly to Fort Lauderdale–Hollywood International Airport, shuttle
- Take the bus from Ann Arbor- Blake Transit Ctr., MI to Detroit Metro Airportbus
- Fly from Detroit (DTW) to Fort Lauderdale–Hollywood International Airport (FLL)plane DTW - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
10h 48m$339–971Bus to Toledo, fly to Key West International Airport
- Take the bus from Ann Arbor Amtrak Station to Toledobus
- Fly from Toledo (TOL) to Key West International Airport (EYW)plane TOL - EYW
17h 51m$227–570
Ann Arbor to Florida Keys by bus and foot
Questions & Answers
The cheapest way to get from Ann Arbor to Florida Keys is to bus which costs $220 - $440 and takes 39h 15m.
The fastest way to get from Ann Arbor to Florida Keys is to bus and fly which takes 9h 38m and costs $190 - $700.
No, there is no direct bus from Ann Arbor to Florida Keys. However, there are services departing from Ann Arbor- Blake Transit Ctr., MI and arriving at Sugarloaf Key - Lower - Sugarloaf Lodge via Rosa Parks Transit Center - Bay 10, Detroit Bus Station, Atlanta Bus Station, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 39h 15m.
The distance between Ann Arbor and Florida Keys is 1281 miles. The road distance is 1477.9 miles.
The best way to get from Ann Arbor to Florida Keys without a car is to bus which takes 39h 15m and costs $220 - $440.
It takes approximately 9h 38m to get from Ann Arbor to Florida Keys, including transfers.
Ann Arbor to Florida Keys bus services, operated by D2A2, depart from Ann Arbor- Blake Transit Ctr., MI station.
Ann Arbor to Florida Keys bus services, operated by D2A2, arrive at Detroit - Grand Circus Park station.
Yes, the driving distance between Ann Arbor to Florida Keys is 1478 miles. It takes approximately 25h 37m to drive from Ann Arbor to Florida Keys.
There are 974+ hotels available in Florida Keys.
What companies run services between Ann Arbor, MI, USA and Florida Keys, FL, USA?
You can take a bus from Ann Arbor- Blake Transit Ctr., MI to Florida Keys via Detroit - Grand Circus Park, Rosa Parks Transit Center - Bay 10, Lafayette & Fifth, Detroit Bus Station, Atlanta Bus Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 39h 15m.
- Website
- delta.com
Flights from Detroit to Key West International Airport via Atlanta
- Ave. Duration
- 5h 31m
- When
- Every day
- Estimated price
- $110–550
Flights from Detroit to Miami International Airport
- Ave. Duration
- 3h 4m
- When
- Every day
- Estimated price
- $140–650
Flights from Detroit to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h 3m
- When
- Every day
- Estimated price
- $140–650
- Website
- aa.com
Flights from Detroit to Key West International Airport via Charlotte
- Ave. Duration
- 5h 27m
- When
- Every day
- Estimated price
- $110–550
Flights from Detroit to Miami International Airport
- Ave. Duration
- 3h 7m
- When
- Every day
- Estimated price
- $140–650
- Website
- jetblue.com
Flights from Detroit to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h
- When
- Every day
- Estimated price
- $140–650
- Website
- allegiantair.com
Flights from Toledo to Key West International Airport via St. Petersburg
- Ave. Duration
- 11h 53m
- When
- Thursday and Sunday
- Estimated price
- $85–390
- Website
- flyfrontier.com
Flights from Detroit to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h 2m
- When
- Every day
- Estimated price
- $140–230
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Toledo to Miami Amtrak Station
- Ave. Duration
- 42h 20m
- Frequency
- Once daily
- Estimated price
- $500–1,100
- Website
- Amtrak
- Phone
- +1 517-333-0400
- [email protected]
- Website
- Michigan Flyer
Bus from Ann Arbor- Blake Transit Ctr., MI to Detroit Metro Airport
- Ave. Duration
- 40 min
- Frequency
- Hourly
- Estimated price
- $7–15
- Website
- Michigan Flyer
- Child 2-16
- $7–9
- Adult
- $10–15
Bus from Ann Arbor- Blake Transit Ctr., MI to Detroit Metro Airport
- Ave. Duration
- 40 min
- Frequency
- Hourly
- Estimated price
- $7–15
- Website
- Michigan Flyer
- Child 2-16
- $7–9
- Adult
- $10–15
Bus from Ann Arbor- Blake Transit Ctr., MI to Detroit Metro Airport
- Ave. Duration
- 40 min
- Frequency
- Hourly
- Estimated price
- $7–15
- Website
- Michigan Flyer
- Child 2-16
- $7–9
- Adult
- $10–15
- Phone
- +1 517-333-0400
- [email protected]
- Website
- D2A2
Bus from Ann Arbor- Blake Transit Ctr., MI to Detroit - Grand Circus Park
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- $8
- Website
- D2A2
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Detroit Bus Station to Atlanta Bus Station
- Ave. Duration
- 16h 20m
- Frequency
- Twice daily
- Estimated price
- $100–200
- Website
- Greyhound
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 17h 20m
- Frequency
- Once daily
- Estimated price
- $95–190
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $18–35
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $18–35
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 13h 30m
- Frequency
- Once daily
- Estimated price
- $95–160
- Schedules at
- Flixbus USA
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Ann Arbor Amtrak Station to Toledo
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- $29–45
- Website
- Amtrak
Bus from Ann Arbor Amtrak Station to Toledo
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- $29–45
- Website
- Amtrak
- Phone
- +1 (305) 289-9997
- [email protected]
- Website
- Keys Shuttle
Shuttle from Miami, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h
- Frequency
- 3 times a day
- Estimated price
- $150–180
- Website
- Keys Shuttle
Shuttle from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $170–200
- Website
- Keys Shuttle
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