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How to get fromAnn Arbor to Great Smoky Mountainsby bus, plane, or car

Find Transport to Great Smoky Mountains

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There are 5 ways to get from Ann Arbor to Great Smoky Mountains by bus, plane, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, fly to Mcghee Tyson Airport, drive

    best
    1. Take the bus from Ann Arbor- Blake Transit Ctr., MI to Detroit Metro Airportbus bus
    2. Fly from Detroit (DTW) to Mcghee Tyson Airport (TYS)plane plane DTW - TYS
    3. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    5h 15m
    $137–783

  2. Drive 554.5 mi

    cheapest
    1. Drive from Ann Arbor to Great Smoky Mountainscar car 554.5 mi
    10h 11m
    $102–147

  3. Bus, drive

    1. Take the bus from Ann Arbor Amtrak Station to Toledobus bus
    2. Take the bus from Toledo Bus Stop to Winston Salem(Trans Center)bus bus
    3. Take the bus from Winston Salem(Trans Center) to Asheville, NCbus bus
    4. Drive from Asheville, NC to Great Smoky Mountainscar car
    21h 43m
    $148–271

  4. Bus, fly to Greenville–Spartanburg International Airport, drive

    1. Take the bus from Ann Arbor- Blake Transit Ctr., MI to Detroit Metro Airportbus bus
    2. Fly from Detroit (DTW) to Greenville–Spartanburg International Airport (GSP)plane plane DTW - GSP
    3. Drive from Greenville–Spartanburg International Airport (GSP) to Great Smoky Mountainscar car
    6h 38m
    $141–702

  5. Bus, fly to Chattanooga Metropolitan Airport, drive

    1. Take the bus from Ann Arbor- Blake Transit Ctr., MI to Detroit Metro Airportbus bus
    2. Fly from Detroit (DTW) to Chattanooga Metropolitan Airport (CHA)plane plane DTW - CHA
    3. Drive from Chattanooga Metropolitan Airport (CHA) to Great Smoky Mountainscar car
    7h 18m
    $174–907

Detroit (DTW) to Mcghee Tyson Airport (TYS) flights

Calendar61Weekly Planes
Duration3h 28mAverage Duration
Ticket$126Cheapest Price
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Questions & Answers

Map of how to get from Ann Arbor to Great Smoky Mountains.ExpandLaunch map view
  • Distance: 532 mi
  • Duration: 5h 15m

What companies run services between Ann Arbor, MI, USA and Great Smoky Mountains, TN, USA?

There is no direct connection from Ann Arbor to Great Smoky Mountains. However, you can take the bus to Detroit Metro Airport, walk to North Terminal, take the bus to McNamara Terminal, walk to Detroit (DTW) airport, fly to Mcghee Tyson Airport (TYS), then drive to Great Smoky Mountains. Alternatively, you can take a bus from Ann Arbor Amtrak Station to Great Smoky Mountains via Toledo Bus Stop, Winston Salem(Trans Center), and Asheville, NC in around 21h 43m.

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