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How to get fromAnn Arbor to Key Westby bus, plane, bus (Greyhound, Flixbus), train, or car

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There are 5 ways to get from Ann Arbor to Key West by bus, plane, bus (Greyhound, Flixbus), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Detroit, fly

    best
    1. Take the bus from Ann Arbor- Blake Transit Ctr., MI to Detroit Metro Airportbus bus
    2. Fly from Detroit (DTW) to Key West International Airport (EYW)plane plane DTW - EYW
    6h 48m
    $128–530

  2. Bus

    1. Take the bus from Ann Arbor- Blake Transit Ctr., MI to Detroit - Grand Circus Parkbus bus
    2. Take the bus from Detroit Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Miami Airport Stationbus bus
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    5. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    40h 2m
    $252–484

  3. Bus, train

    1. Take the bus from Ann Arbor Amtrak Station to Toledobus bus
    2. Take the train from Toledo to Miami Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    2d 4h
    $625–1,315

  4. Drive 1,484.7 mi

    1. Drive from Ann Arbor to Key Westcar car 1,484.7 mi
    26h
    $271–392

  5. Bus to Toledo, fly

    1. Take the bus from Ann Arbor Amtrak Station to Toledobus bus
    2. Fly from Toledo (TOL) to Key West International Airport (EYW)plane plane TOL - EYW
    19h 1m
    $170–505

Ann Arbor to Key West by bus and foot

Calendar14Weekly Services
Duration40h 2mAverage Duration
Ticket$252Cheapest Price
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Questions & Answers

Map of how to get from Ann Arbor to Key West.ExpandLaunch map view
  • Distance: 1,254.4 mi
  • Duration: 6h 48m

What companies run services between Ann Arbor, MI, USA and Key West, FL, USA?

You can take a bus from Ann Arbor- Blake Transit Ctr., MI to N Roosevelt & 3rd Street via Detroit - Grand Circus Park, Rosa Parks Transit Center - Bay 10, Lafayette & Fifth, Detroit Bus Station, Atlanta Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 40h 2m.

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