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How to get fromAnn Arbor to La Crosseby train (Amtrak), bus (Flixbus), car, bus, plane, bus (Amtrak), or train

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There are 8 ways to get from Ann Arbor to La Crosse by train (Amtrak), bus (Flixbus), car, bus, plane, bus (Amtrak), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Ann Arbor Amtrak Station to Chicago Union Stationtrain train Wolverine
    2. Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain train Empire Builder / ...
    10h 17m
    $169–350

  2. Drive 521.6 mi

    cheapest
    1. Drive from Ann Arbor to La Crossecar car 521.6 mi
    8h 41m
    $96–138

  3. Bus

    1. Take the bus from Ann Arbor to Milwaukee Intermodal Stationbus bus FlixBus 2550
    2. Take the bus from Milwaukee to La Crossebus bus Jefferson 966 / ...
    11h 25m
    $109–170

  4. Bus, fly to La Crosse

    1. Take the bus from Ann Arbor- Blake Transit Ctr., MI to Detroit Metro Airportbus bus
    2. Fly from Detroit (DTW) to La Crosse (LSE)plane plane DTW - LSE
    6h 23m
    $96–450

  5. Bus via Chicago

    1. Take the bus from Ann Arbor Amtrak Station to Chicago Union Stationbus bus
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to La Crossebus bus
    12h 37m
    $143–226

  6. Bus, fly to Dane County Regional Airport-Truax Field

    1. Take the bus from Ann Arbor- Blake Transit Ctr., MI to Detroit Metro Airportbus bus
    2. Fly from Detroit (DTW) to Dane County Regional Airport-Truax Field (MSN)plane plane DTW - MSN
    3. Take the bus from Madison to UW La Crossebus bus
    7h 14m
    $134–674

  7. Bus, fly to Minneapolis–Saint Paul International Airport, train

    1. Take the bus from Ann Arbor- Blake Transit Ctr., MI to Detroit Metro Airportbus bus
    2. Fly from Detroit (DTW) to Minneapolis–Saint Paul International Airport (MSP)plane plane DTW - MSP
    3. Take the train from St. Paul-Minneapolis to La Crosse Amtrak Stationtrain train
    8h 6m
    $519–1,305

  8. Bus, fly to Appleton International Airport

    1. Take the bus from Ann Arbor- Blake Transit Ctr., MI to Detroit Metro Airportbus bus
    2. Fly from Detroit (DTW) to Appleton International Airport (ATW)plane plane DTW - ATW
    3. Take the bus from Appleton Valley Transit to La Crosse Grand River Stationbus bus
    8h 40m
    $167–825

Ann Arbor to La Crosse by train (Amtrak)

Calendar21Weekly Trains
Duration10h 17mAverage Duration
Ticket$169Cheapest Price
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Questions & Answers

Map of how to get from Ann Arbor to La Crosse.ExpandLaunch map view
  • Distance: 522.3 mi
  • Duration: 10h 17m

What companies run services between Ann Arbor, MI, USA and La Crosse, WI, USA?

You can take a train from Ann Arbor Amtrak Station to La Crosse Amtrak Station via Chicago Union Station in around 10h 17m. Alternatively, you can take a bus from Ann Arbor to La Crosse via Milwaukee Intermodal Station and Milwaukee in around 11h 25m.

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