There are 6 ways to get from Ann Arbor to Lancaster by bus, plane, bus (Amtrak, Flixbus), train, car, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, fly to Harrisburg International Airport, line 18 bus
best- Take the bus from Ann Arbor- Blake Transit Ctr., MI to Detroit Metro Airportbus
- Fly from Detroit (DTW) to Harrisburg International Airport (MDT)plane DTW - MDT
- Take the bus from AMTRAK ETown to W. Chestnut & Water St.bus
7h 22mBus
cheapest- Take the bus from Ann Arbor to Detroit Bus Stationbus Greyhound US0160
- Take the bus from Detroit Bus Station to Harrisburg Bus Stationbus Greyhound US0420
18h 7m$86–174Bus via State College Airport (SCE)
- Take the bus from Ann Arbor Amtrak Station to Toledobus
- Take the bus from Toledo Bus Stop to State College Regional Airportbus
- Take the bus from State College Regional Airport to Harrisburg Bus Stationbus
16h 32m$107–183Bus, train (Amtrak)
- Take the bus from Ann Arbor Amtrak Station to Toledobus
- Take the train from Toledo to Pittsburgh Amtrak Stationtrain
- Take the train from Pittsburgh Amtrak Station to Elizabethtown Amtrak Stationtrain
17h 15m$188–396Drive 509.7 mi
- Drive from Ann Arbor to Lancastercar 509.7 mi
8h 39m$93–135Bus, fly to Philadelphia International Airport, train
- Take the bus from Ann Arbor- Blake Transit Ctr., MI to Detroit Metro Airportbus
- Fly from Detroit (DTW) to Philadelphia International Airport (PHL)plane DTW - PHL
- Take the train from 30th Street Station to Elizabethtown Amtrak Stationtrain
8h 30m$167–490
Ann Arbor to Lancaster by bus and train
Questions & Answers
The cheapest way to get from Ann Arbor to Lancaster is to bus which costs $85 - $180 and takes 18h 7m.
The fastest way to get from Ann Arbor to Lancaster is to bus and fly and train which takes 8h 30m and costs $160 - $490.
No, there is no direct bus from Ann Arbor station to Lancaster. However, there are services departing from Ann Arbor Amtrak Station and arriving at W. Chestnut & Water St. via Toledo Bus Stop, State College Regional Airport and AMTRAK ETown. The journey, including transfers, takes approximately 16h 32m.
The distance between Ann Arbor and Lancaster is 452 miles. The road distance is 512.7 miles.
The best way to get from Ann Arbor to Lancaster without a car is to bus via State College Airport (SCE) which takes 16h 32m and costs $100 - $190.
It takes approximately 7h 22m to get from Ann Arbor to Lancaster, including transfers.
Ann Arbor to Lancaster bus services, operated by Amtrak, depart from Ann Arbor Amtrak Station.
Ann Arbor to Lancaster bus services, operated by Amtrak, arrive at Toledo station.
Yes, the driving distance between Ann Arbor to Lancaster is 513 miles. It takes approximately 8h 39m to drive from Ann Arbor to Lancaster.
Book your Ann Arbor to Lancaster bus tickets online with Omio.
What companies run services between Ann Arbor, MI, USA and Lancaster, PA, USA?
You can take a bus from Ann Arbor Amtrak Station to W. Chestnut & Water St. via Toledo Bus Stop, State College Regional Airport, Harrisburg Bus Station, Harrisburg, Elizabethtown Amtrak Station, and AMTRAK ETown in around 16h 32m.
- Website
- delta.com
Flights from Detroit to Harrisburg International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $65–390
Flights from Detroit to Philadelphia International Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- $95–600
- Website
- aa.com
Flights from Detroit to Philadelphia International Airport
- Ave. Duration
- 1h 43m
- When
- Every day
- Estimated price
- $95–600
- Website
- united.com
Flights from Detroit to Harrisburg International Airport via Washington Dulles
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- $70–420
- Website
- flyfrontier.com
Flights from Detroit to Philadelphia International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $130–220
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Toledo to Pittsburgh Amtrak Station
- Ave. Duration
- 5h 16m
- Frequency
- Once daily
- Estimated price
- $75–170
- Website
- Amtrak
Train from Pittsburgh Amtrak Station to Elizabethtown Amtrak Station
- Ave. Duration
- 5h 52m
- Frequency
- Once daily
- Estimated price
- $80–180
- Website
- Amtrak
Train from 30th Street Station to Elizabethtown Amtrak Station
- Ave. Duration
- 1h 32m
- Frequency
- Every 2 hours
- Estimated price
- $27–60
- Website
- Amtrak
- Phone
- +1 517-333-0400
- [email protected]
- Website
- Michigan Flyer
Bus from Ann Arbor- Blake Transit Ctr., MI to Detroit Metro Airport
- Ave. Duration
- 40 min
- Frequency
- Hourly
- Estimated price
- $7–15
- Website
- Michigan Flyer
- Child 2-16
- $7–9
- Adult
- $10–15
Bus from Ann Arbor- Blake Transit Ctr., MI to Detroit Metro Airport
- Ave. Duration
- 40 min
- Frequency
- Hourly
- Estimated price
- $7–15
- Website
- Michigan Flyer
- Child 2-16
- $7–9
- Adult
- $10–15
- Phone
- +1 717-397-4246
- Website
- Red Rose Transit
Bus from AMTRAK ETown to W. Chestnut & Water St.
- Ave. Duration
- 57 min
- Frequency
- Every 4 hours
- Website
- Red Rose Transit
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Ann Arbor Amtrak Station to Toledo
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- $30–50
- Website
- Amtrak
Bus from Ann Arbor Amtrak Station to Toledo
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- $30–50
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Toledo Bus Stop to State College Regional Airport
- Ave. Duration
- 7h 25m
- Frequency
- Twice daily
- Estimated price
- $55–100
- Schedules at
- Flixbus USA
Bus from State College Regional Airport to Harrisburg Bus Station
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- $14–25
- Schedules at
- Flixbus USA
Bus from Ann Arbor to Detroit Bus Station
- Ave. Duration
- 45 min
- Frequency
- Once daily
- Estimated price
- $6–11
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Ann Arbor to Detroit Bus Station
- Ave. Duration
- 50 min
- Frequency
- 5 times a day
- Estimated price
- $6–12
- Website
- Greyhound
Bus from Detroit Bus Station to Harrisburg Bus Station
- Ave. Duration
- 13h 5m
- Frequency
- Twice daily
- Estimated price
- $75–150
- Website
- Greyhound
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Ann Arbor to Detroit Bus Station
- Ave. Duration
- 40 min
- Frequency
- Twice daily
- Estimated price
- $4–35
- Website
- Barons Bus
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