There are 7 ways to get from Ann Arbor to Louisville by bus, plane, bus (Amtrak, Greyhound), car, or bus (Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Detroit, fly to Louisville International Airport
best- Take the bus from Blake Transit Center to DTW McNamara Terminalbus
- Fly from Detroit (DTW) to Louisville International Airport (SDF)plane DTW - SDF
4h 17m$88–568Drive 346.2 mi
cheapest- Drive from Ann Arbor to Louisvillecar 346.2 mi
5h 52m$64–92Bus
- Take the bus from Ann Arbor Amtrak Station to Toledobus Amtrak Thruway Connecting Service
- Take the bus from Toledo Bus Stop to Louisville Bus Stationbus Greyhound US0135 / ...
9h$79–137Bus to Detroit, fly to Blue Grass Airport, drive
- Take the bus from Blake Transit Center to DTW McNamara Terminalbus
- Fly from Detroit (DTW) to Blue Grass Airport (LEX)plane DTW - LEX
- Drive from Lexington-Airport-LEX to Louisvillecar
4h 22m$140–834Drive to Capital Region International Airport, fly to Louisville International Airport
- Drive from Ann Arbor to Lansing-Airport-LANcar
- Fly from Capital Region International Airport (LAN) to Louisville International Airport (SDF)plane LAN - SDF
6h 9m$109–621Bus to Detroit, fly to Covington, bus
- Take the bus from Blake Transit Center to DTW McNamara Terminalbus
- Fly from Detroit (DTW) to Covington (CVG)plane DTW - CVG
- Take the bus from Cincinnati to Louisvillebus
6h 42m$918–1,362Bus via Columbus
- Take the bus from Ann Arbor Amtrak Station to Toledobus
- Take the bus from Toledo Bus Stop to N Wilson Rd & Ferrell Pl - Columbusbus
- Take the bus from N Wilson Rd & Ferrell Pl - Columbus to Louisville, KY Bus Stationbus
10h 55m$66–157
Ann Arbor to Louisville by bus
Questions & Answers
The cheapest way to get from Ann Arbor to Louisville is to drive which costs $60 - $95 and takes 5h 52m.
The fastest way to get from Ann Arbor to Louisville is to bus and fly which takes 4h 17m and costs $85 - $600.
No, there is no direct bus from Ann Arbor station to Louisville station. However, there are services departing from Ann Arbor Amtrak Station and arriving at Louisville Bus Station via Toledo Bus Stop. The journey, including transfers, takes approximately 9h.
The distance between Ann Arbor and Louisville is 339 miles. The road distance is 348.2 miles.
The best way to get from Ann Arbor to Louisville without a car is to bus which takes 9h and costs $75 - $140.
It takes approximately 4h 17m to get from Ann Arbor to Louisville, including transfers.
Ann Arbor to Louisville bus services, operated by Amtrak, depart from Ann Arbor Amtrak Station.
Ann Arbor to Louisville bus services, operated by Amtrak, arrive at Toledo station.
Yes, the driving distance between Ann Arbor to Louisville is 348 miles. It takes approximately 5h 52m to drive from Ann Arbor to Louisville.
Book your Ann Arbor to Louisville bus tickets online with Omio.
What companies run services between Ann Arbor, MI, USA and Louisville, KY, USA?
You can take a bus from Ann Arbor Amtrak Station to Louisville Bus Station via Toledo Bus Stop in around 9h.
- Website
- delta.com
Flights from Detroit to Louisville International Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $80–550
Flights from Detroit to Blue Grass Airport
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- $120–800
Flights from Capital Region International Airport to Louisville International Airport via Detroit
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- $95–600
Flights from Detroit to Covington
- Ave. Duration
- 1h 16m
- When
- Every day
- Estimated price
- $75–550
- Website
- aa.com
Flights from Capital Region International Airport to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 4h 37m
- When
- Every day
- Estimated price
- $100–600
Flights from Capital Region International Airport to Louisville International Airport via Reagan Washington
- Ave. Duration
- 4h 59m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $160–800
- Website
- southwest.com
Flights from Detroit to Louisville International Airport via Nashville
- Ave. Duration
- 3h 45m
- When
- Sunday
- Estimated price
- $110–650
Flights from Capital Region International Airport to Louisville International Airport via Orlando
- Ave. Duration
- 6h 29m
- When
- Saturday
- Estimated price
- $410–2,000
- Website
- united.com
Flights from Capital Region International Airport to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 5h 56m
- When
- Sunday
- Estimated price
- $100–600
- Phone
- +1 517-333-0400
- [email protected]
- Website
- michiganflyer.com
Bus from Blake Transit Center to DTW McNamara Terminal
- Ave. Duration
- 40 min
- Frequency
- Every 4 hours
- Estimated price
- $7–16
- Website
- https://www.michiganflyer.com/
- Child 2-16
- $7–9
- Adult
- $11–16
Bus from Blake Transit Center to DTW McNamara Terminal
- Ave. Duration
- 40 min
- Frequency
- Every 4 hours
- Estimated price
- $7–16
- Website
- https://www.michiganflyer.com/
- Child 2-16
- $7–9
- Adult
- $11–16
Bus from Blake Transit Center to DTW McNamara Terminal
- Ave. Duration
- 40 min
- Frequency
- Every 4 hours
- Estimated price
- $7–16
- Website
- https://www.michiganflyer.com/
- Child 2-16
- $7–9
- Adult
- $11–16
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Ann Arbor Amtrak Station to Toledo
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- $30–50
- Website
- https://www.amtrak.com/home.html
Bus from Ann Arbor Amtrak Station to Toledo
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- $30–50
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Toledo Bus Stop to Louisville Bus Station
- Ave. Duration
- 5h 50m
- Frequency
- Twice daily
- Estimated price
- $45–90
- Website
- https://www.greyhound.com/
- Website
- greyhound.com
Bus from Toledo Bus Stop to Louisville Bus Station
- Ave. Duration
- 5h 50m
- Frequency
- Once daily
- Schedules at
- greyhound.com
- Website
- example.com
Bus from Cincinnati to Louisville
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Schedules at
- example.com
Bus from Toledo Bus Stop to N Wilson Rd & Ferrell Pl - Columbus
- Ave. Duration
- 3h 10m
- Frequency
- Once daily
- Schedules at
- example.com
Bus from N Wilson Rd & Ferrell Pl - Columbus to Louisville, KY Bus Station
- Ave. Duration
- 4h
- Frequency
- Once daily
- Schedules at
- example.com
- Phone
- +1 888-378-3823
- [email protected]
- Website
- baronsbus.com
Bus from Cincinnati to Louisville
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $9–45
- Website
- https://baronsbus.com
Bus from Toledo Bus Stop to N Wilson Rd & Ferrell Pl - Columbus
- Ave. Duration
- 2h 40m
- Frequency
- Once daily
- Estimated price
- $12–50
- Website
- https://baronsbus.com
Bus from N Wilson Rd & Ferrell Pl - Columbus to Louisville, KY Bus Station
- Ave. Duration
- 4h 5m
- Frequency
- Twice daily
- Estimated price
- $20–60
- Website
- https://baronsbus.com
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