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How to get fromAnn Arbor to Orangeburgby bus, plane, taxi, bus (Greyhound, Flixbus), train, or car

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There are 6 ways to get from Ann Arbor to Orangeburg by bus, plane, taxi, bus (Greyhound, Flixbus), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, fly to Columbia, taxi

    best
    1. Take the bus from Ann Arbor- Blake Transit Ctr., MI to Detroit Metro Airportbus bus
    2. Fly from Detroit (DTW) to Columbia (CAE)plane plane DTW - CAE
    3. Take the taxi from Columbia-Airport-CAE to Orangeburgtaxi taxi
    6h 19m
    $337–1,367

  2. Drive 735.6 mi

    cheapest
    1. Drive from Ann Arbor to Orangeburgcar car 735.6 mi
    12h 58m
    $135–194

  3. Bus

    1. Take the bus from Ann Arbor to Detroit Bus Stationbus bus
    2. Take the bus from Detroit Bus Station to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte Bus Station to Orangeburgbus bus
    22h 43m
    $139–272

  4. Bus, train (Amtrak)

    1. Take the bus from Ann Arbor Amtrak Station to Toledobus bus Amtrak Thruway Connecting Service
    2. Take the train from Toledo to Denmark Amtrak Stationtrain train Floridian
    29h 23m
    $448–877

  5. Bus, fly to Savannah, train

    1. Take the bus from Ann Arbor- Blake Transit Ctr., MI to Detroit Metro Airportbus bus
    2. Fly from Detroit (DTW) to Savannah (SAV)plane plane DTW - SAV
    3. Take the train from Savannah Station to Denmark Amtrak Stationtrain train
    7h 4m
    $260–857

  6. Bus, fly to Charlotte Douglas International Airport

    1. Take the bus from Ann Arbor- Blake Transit Ctr., MI to Detroit Metro Airportbus bus
    2. Fly from Detroit (DTW) to Charlotte Douglas International Airport (CLT)plane plane DTW - CLT
    3. Take the bus from Charlotte Bus Station to Orangeburgbus bus
    9h 26m
    $154–733

Detroit (DTW) to Columbia (CAE) flights

Calendar129Weekly Planes
Duration4h 58mAverage Duration
Ticket$211Cheapest Price
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Questions & Answers

Map of how to get from Ann Arbor to Orangeburg.ExpandLaunch map view
  • Distance: 652 mi
  • Duration: 6h 19m

What companies run services between Ann Arbor, MI, USA and Orangeburg, SC, USA?

You can take a bus from Ann Arbor to Orangeburg via Detroit Bus Station, Charlotte Bus Station, and Orangeburg in around 22h 43m.

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