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How to get fromAnn Arbor to Sioux Fallsby bus, plane, train, car, bus (Amtrak, Greyhound), or bus (Flixbus)

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There are 7 ways to get from Ann Arbor to Sioux Falls by bus, plane, train, car, bus (Amtrak, Greyhound), or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, fly

    best
    1. Take the bus from Blake Transit Center to DTW McNamara Terminalbus bus
    2. Fly from Detroit (DTW) to Sioux Falls (FSD)plane plane DTW - FSD
    6h 59m
    $99–487

  2. Train, bus via Saint Paul

    1. Take the train from Ann Arbor Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    3. Take the bus from St. Paul to Albert Leabus bus
    4. Take the bus from Albert Lea to Sioux Fallsbus bus
    20h 8m
    $297–566

  3. Train, bus

    1. Take the train from Ann Arbor Amtrak Station to Chicago Union Stationtrain train
    2. Take the bus from Chicago Bus Station to Omaha, NEbus bus
    3. Take the bus from Omaha to Sioux Fallsbus bus
    21h 20m
    $201–386

  4. Drive 781.6 mi

    1. Drive from Ann Arbor to Sioux Fallscar car 781.6 mi
    14h 12m
    $143–206

  5. Bus

    1. Take the bus from Ann Arbor Amtrak Station to Chicago Union Stationbus bus
    2. Take the bus from Chicago Bus Station to Omaha, NEbus bus
    3. Take the bus from Omaha to Sioux Fallsbus bus
    21h 41m
    $207–345

  6. Train, bus #2

    1. Take the train from Ann Arbor Amtrak Station to Chicago Union Stationtrain train
    2. Take the bus from Chicago Bus Station to Minneapolis Bus Stationbus bus
    3. Take the bus from Minneapolis to Sioux Fallsbus bus
    21h 50m
    $211–391

  7. Bus via Minneapolis

    1. Take the bus from Ann Arbor to Milwaukee Mitchell Airportbus bus
    2. Take the bus from Milwaukee Mitchell Airport to Minneapolis Bus Stationbus bus
    3. Take the bus from Minneapolis to Sioux Fallsbus bus
    23h 8m
    $175–288

Detroit (DTW) to Sioux Falls (FSD) flights

Calendar115Weekly Planes
Duration5h 36mAverage Duration
Ticket$92Cheapest Price
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Questions & Answers

Map of how to get from Ann Arbor to Sioux Falls.ExpandLaunch map view
  • Distance: 715 mi
  • Duration: 6h 59m

What companies run services between Ann Arbor, MI, USA and Sioux Falls, SD, USA?

You can take a bus from Ann Arbor Amtrak Station to The Bus Stop via Chicago Union Station, Chicago Bus Station, Omaha, Sioux Falls, and Maple/Career NE corner in around 21h 41m.

Airlines
Train operators
Bus operators

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