There are 5 ways to get from Ann Arbor to Winston-Salem by bus, plane, bus (Greyhound, Flixbus), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Detroit, fly to Piedmont Triad International Airport
best- Take the bus from Blake Transit Center to DTW McNamara Terminalbus
- Fly from Detroit (DTW) to Piedmont Triad International Airport (GSO)plane DTW - GSO
4h 30m$146–738Bus
cheapest- Take the bus from Ann Arbor to Detroit Bus Stationbus Greyhound US0160
- Take the bus from Detroit Bus Station to Winston Salem(Trans Center)bus Greyhound US0140
15h 50m$96–192Drive 549.5 mi
- Drive from Ann Arbor to Winston-Salemcar 549.5 mi
9h 55m$101–145Drive to Capital Region International Airport, fly to Piedmont Triad International Airport
- Drive from Ann Arbor to Lansing-Airport-LANcar
- Fly from Capital Region International Airport (LAN) to Piedmont Triad International Airport (GSO)plane LAN - GSO
7h 20m$162–791Bus to Detroit, fly to Charlotte Douglas International Airport, bus
- Take the bus from Blake Transit Center to DTW McNamara Terminalbus
- Fly from Detroit (DTW) to Charlotte Douglas International Airport (CLT)plane DTW - CLT
- Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus
6h 40m$128–711
Ann Arbor to Winston-Salem by bus
Questions & Answers
The cheapest way to get from Ann Arbor to Winston-Salem is to bus which costs $95 - $200 and takes 15h 50m.
The fastest way to get from Ann Arbor to Winston-Salem is to bus and fly which takes 4h 30m and costs $140 - $750.
No, there is no direct bus from Ann Arbor to Winston-Salem. However, there are services departing from Ann Arbor and arriving at Winston Salem(Trans Center) via Detroit Bus Station. The journey, including transfers, takes approximately 15h 50m.
The distance between Ann Arbor and Winston-Salem is 512 miles. The road distance is 552.7 miles.
The best way to get from Ann Arbor to Winston-Salem without a car is to bus which takes 15h 50m and costs $95 - $200.
It takes approximately 4h 30m to get from Ann Arbor to Winston-Salem, including transfers.
Ann Arbor to Winston-Salem bus services, operated by Greyhound USA, depart from Ann Arbor station.
Ann Arbor to Winston-Salem bus services, operated by Greyhound USA, arrive at Detroit Bus Station.
Yes, the driving distance between Ann Arbor to Winston-Salem is 553 miles. It takes approximately 9h 55m to drive from Ann Arbor to Winston-Salem.
Book your Ann Arbor to Winston-Salem bus tickets online with Omio and FlixBus.
What companies run services between Ann Arbor, MI, USA and Winston-Salem, NC, USA?
You can take a bus from Ann Arbor to Winston Salem(Trans Center) via Detroit Bus Station in around 15h 50m.
- Website
- delta.com
Flights from Detroit to Piedmont Triad International Airport
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- $120–700
Flights from Detroit to Piedmont Triad International Airport via Atlanta
- Ave. Duration
- 4h 14m
- When
- Every day
- Estimated price
- $180–900
Flights from Capital Region International Airport to Piedmont Triad International Airport via Detroit
- Ave. Duration
- 6h 56m
- When
- Every day
- Estimated price
- $130–750
Flights from Detroit to Charlotte Douglas International Airport
- Ave. Duration
- 1h 49m
- When
- Every day
- Estimated price
- $110–650
- Website
- aa.com
Flights from Detroit to Piedmont Triad International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- $130–750
Flights from Detroit to Piedmont Triad International Airport via Philadelphia
- Ave. Duration
- 4h 24m
- When
- Every day
- Estimated price
- $170–850
Flights from Capital Region International Airport to Piedmont Triad International Airport via Chicago O'Hare
- Ave. Duration
- 6h 55m
- When
- Every day
- Estimated price
- $170–850
Flights from Detroit to Charlotte Douglas International Airport
- Ave. Duration
- 1h 53m
- When
- Every day
- Estimated price
- $110–650
- Website
- united.com
Flights from Detroit to Piedmont Triad International Airport via Washington Dulles
- Ave. Duration
- 4h 4m
- When
- Every day
- Estimated price
- $140–750
Flights from Capital Region International Airport to Piedmont Triad International Airport via Chicago O'Hare
- Ave. Duration
- 8h 37m
- When
- Every day
- Estimated price
- $170–850
- Phone
- +1 517-333-0400
- [email protected]
- Website
- michiganflyer.com
Bus from Blake Transit Center to DTW McNamara Terminal
- Ave. Duration
- 40 min
- Frequency
- Every 4 hours
- Estimated price
- $7–16
- Website
- https://www.michiganflyer.com/
- Child 2-16
- $7–9
- Adult
- $11–16
Bus from Blake Transit Center to DTW McNamara Terminal
- Ave. Duration
- 40 min
- Frequency
- Every 4 hours
- Estimated price
- $7–16
- Website
- https://www.michiganflyer.com/
- Child 2-16
- $7–9
- Adult
- $11–16
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Ann Arbor to Detroit Bus Station
- Ave. Duration
- 50 min
- Frequency
- 3 times a day
- Estimated price
- $6–12
- Website
- https://www.greyhound.com/
Bus from Detroit Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 14h 15m
- Frequency
- Once daily
- Estimated price
- $90–180
- Website
- https://www.greyhound.com/
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $11–23
- Website
- https://www.greyhound.com/
- Website
- greyhound.com
Bus from Ann Arbor to Detroit Bus Station
- Ave. Duration
- 55 min
- Frequency
- 3 times a day
- Schedules at
- greyhound.com
Bus from Detroit Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 14h
- Frequency
- Once daily
- Schedules at
- greyhound.com
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Schedules at
- greyhound.com
- Phone
- +1 888-378-3823
- [email protected]
- Website
- baronsbus.com
Bus from Ann Arbor to Detroit Bus Station
- Ave. Duration
- 40 min
- Frequency
- Twice daily
- Estimated price
- $4–35
- Website
- https://baronsbus.com
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $7–40
- Website
- https://baronsbus.com
- Website
- example.com
Bus from Ann Arbor to Detroit Bus Station
- Ave. Duration
- 45 min
- Frequency
- Once daily
- Schedules at
- example.com
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Ann Arbor to Detroit Bus Station
- Ave. Duration
- 45 min
- Frequency
- 5 times a week
- Estimated price
- $6–12
- Schedules at
- flixbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
There are 142+ hotels available in Winston-Salem.







