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How to get fromAnnapolis to Louisvilleby bus, plane, bus (Flixbus, Greyhound, Amtrak), train, car, or subway

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There are 7 ways to get from Annapolis to Louisville by bus, plane, bus (Flixbus, Greyhound, Amtrak), train, car, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Ronald Reagan Washington National Airport, fly to Louisville International Airport

    best
    1. Take the bus from Annapolis to Washington Union Stationbus bus
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Louisville International Airport (SDF)plane plane DCA - SDF
    5h 18m
    $170–1,017

  2. Bus to Ronald Reagan Washington National Airport, fly to Blue Grass Airport, drive

    cheapest
    1. Take the bus from Annapolis to Washington Union Stationbus bus
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Blue Grass Airport (LEX)plane plane DCA - LEX
    3. Drive from Lexington-Airport-LEX to Louisvillecar car
    5h 5m
    $107–583

  3. Bus

    1. Take the bus from Annapolis to Washington Union Stationbus bus
    2. Take the bus from Washington Union Station to Nashville Bus Stationbus bus
    3. Take the bus from Nashville to Louisville, KYbus bus
    21h 30m
    $145–237

  4. Bus, train

    1. Take the bus from Annapolis to Washington Union Stationbus bus
    2. Take the train from Washington Union Station to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    22h 56m
    $417–702

  5. Drive  611.6 mi

    1. Drive from Annapolis to Louisvillecar car 611.6 mi
    10h 40m
    $112–162

  6. Line 70 bus to Baltimore-Washington International Airport, fly to Louisville International Airport

    1. Take the bus from COLLEGE AVE & BLADEN ST eb to Cromwell Light Rail Station Bay 1bus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to Louisville International Airport (SDF)plane plane BWI - SDF
    5h 38m
    $137–763

  7. Bus, subway to Washington Dulles International Airport, fly to Louisville International Airport

    1. Take the bus from Annapolis to Washington Union Stationbus bus
    2. Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    3. Fly from Washington Dulles International Airport (IAD) to Louisville International Airport (SDF)plane plane IAD - SDF
    5h 47m
    $110–666

Annapolis to Louisville by bus

Calendar7Weekly Buses
Duration21h 30mAverage Duration
Ticket$145Cheapest Price
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Comparing Your Travel Options

Map of how to get from Annapolis to Louisville.ExpandLaunch map view
  • Distance: 515.1 mi
  • Duration: 5h 18m

What companies run services between Annapolis, MD, USA and Louisville, KY, USA?

You can take a bus from Annapolis to Louisville, KY via Washington Union Station and Nashville in around 21h 30m.

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