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How to get fromAnnapolis to Senecaby bus, plane, taxi, train, car, or subway

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There are 7 ways to get from Annapolis to Seneca by bus, plane, taxi, train, car, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Ronald Reagan Washington National Airport, fly to Greenville–Spartanburg International Airport, taxi

    best
    1. Take the bus from Annapolis to Washington Union Stationbus bus
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Greenville–Spartanburg International Airport (GSP)plane plane DCA - GSP
    3. Take the taxi from Greenville–Spartanburg International Airport (GSP) to Senecataxi taxi
    4h 57m
    $268–984

  2. Drive  539.2 mi

    cheapest
    1. Drive from Annapolis to Senecacar car 539.2 mi
    10h 28m
    $99–143

  3. Bus, train

    1. Take the bus from Annapolis to Washington Union Stationbus bus FlixBus 2601 / ...
    2. Take the train from Washington Union Station to Clemson Amtrak Stationtrain train Crescent
    13h 34m
    $158–337

  4. Bus, taxi

    1. Take the bus from Annapolis to Washington Union Stationbus bus
    2. Take the bus from Washington Union Station to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus bus
    4. Take the taxi from Taqueria Guadalajara - Greenville to Senecataxi taxi
    14h 26m
    $184–278

  5. Line 70 bus to Baltimore-Washington International Airport, fly to Greenville–Spartanburg International Airport, taxi

    1. Take the bus from COLLEGE AVE & BLADEN ST eb to Cromwell Light Rail Station Bay 1bus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to Greenville–Spartanburg International Airport (GSP)plane plane BWI - GSP
    3. Take the taxi from Greenville–Spartanburg International Airport (GSP) to Senecataxi taxi
    5h 19m
    $231–780

  6. Bus, subway to Washington Dulles International Airport, fly to Greenville–Spartanburg International Airport, taxi

    1. Take the bus from Annapolis to Washington Union Stationbus bus
    2. Take the subway from Farragut West, Blue/Orange/Silver Line Track 2 Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    3. Fly from Washington Dulles International Airport (IAD) to Greenville–Spartanburg International Airport (GSP)plane plane IAD - GSP
    4. Take the taxi from Greenville–Spartanburg International Airport (GSP) to Senecataxi taxi
    5h 30m
    $218–683

  7. Bus to Ronald Reagan Washington National Airport, fly to Asheville Regional Airport, drive

    1. Take the bus from Annapolis to Washington Union Stationbus bus
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Asheville Regional Airport (AVL)plane plane DCA - AVL
    3. Drive from Asheville-Airport-AVL to Senecacar car
    5h 43m
    $105–583

Ronald Reagan Washington National Airport (DCA) to Greenville–Spartanburg International Airport (GSP) flights

Calendar77Weekly Planes
Duration3h 20mAverage Duration
Ticket$131Cheapest Price
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Comparing Your Travel Options

Map of how to get from Annapolis to Seneca.ExpandLaunch map view
  • Distance: 481.8 mi
  • Duration: 4h 57m

What companies run services between Annapolis, MD, USA and Seneca, SC, USA?

There is no direct connection from Annapolis to Seneca. However, you can take the bus to Washington Union Station, walk to Union Station, Red Line Center Platform, take the subway to Gallery Place, Red Line Track 2 Platform, walk to Gallery Place, Green/Yellow Line Center Platform, take the subway to Ronald Reagan Washington National Airport, Yellow/Blue Line Track 2 Platform-Trains South Toward Alexandria, walk to Ronald Reagan Washington National Airport (DCA) airport, fly to Greenville–Spartanburg International Airport (GSP), then take the taxi to Seneca. Alternatively, you can take a bus from Annapolis to Seneca via Washington Union Station, Washington Union Station, and Clemson Amtrak Station in around 13h 34m.

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