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How to get fromAntigua Guatemala to Panama City Beachby plane, bus (Greyhound), car, or bus

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There are 10 ways to get from Antigua Guatemala to Panama City Beach by plane, bus (Greyhound), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Northwest Florida Beaches International Airport

    best
    1. Fly from La Aurora International Airport (GUA) to Northwest Florida Beaches International Airport (ECP)plane plane GUA - ECP
    10h 40m
    $182–627

  2. Fly to Pensacola International Airport, bus

    cheapest
    1. Fly from La Aurora International Airport (GUA) to Pensacola International Airport (PNS)plane plane GUA - PNS
    2. Take the bus from Pensacola Airport to Panama City Beach Bus Stationbus bus
    13h 23m
    $135–522

  3. Bus

    1. Take the bus from Antigua Guatemala to Panajachelbus bus
    2. Take the bus from Panajachel to San Cristóbal de las Casasbus bus
    3. Take the bus from San Cristóbal de las Casas to Coatzacoalcosbus bus
    4. Take the bus from Coatzacoalcos to Reynosabus bus
    5. Take the bus from Hidalgo International Bridge to Houston Bus Stationbus bus
    6. Take the bus from Houston Bus Station to Panama City Beach Bus Stationbus bus
    2d 9h
    $380–638

  4. Drive 2,140.1 mi

    1. Drive from Antigua Guatemala to Panama City Beachcar car 2,140.1 mi
    43h 40m
    $416–600

  5. Fly to Destin–Fort Walton Beach Airport, drive

    1. Fly from La Aurora International Airport (GUA) to Destin–Fort Walton Beach Airport (VPS)plane plane GUA - VPS
    2. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama City Beachcar car
    11h 52m
    $142–578

  6. Fly to Dothan Regional Airport, drive

    1. Fly from La Aurora International Airport (GUA) to Dothan Regional Airport (DHN)plane plane GUA - DHN
    2. Drive from Dothan Regional Airport (DHN) to Panama City Beachcar car
    12h 16m
    $149–588

  7. Fly to Tallahassee, bus

    1. Fly from La Aurora International Airport (GUA) to Tallahassee (TLH)plane plane GUA - TLH
    2. Take the bus from Tallahassee to Panama City Beach Bus Stationbus bus
    13h 35m
    $209–781

  8. Bus via Santiago de Querétaro

    1. Take the bus from Antigua Guatemala to San Cristóbal de las Casasbus bus
    2. Take the bus from San Cristóbal de las Casas to Pueblabus bus
    3. Take the bus from Puebla CAPU to Terminal de Autobuses de Querétaro Acceso 1bus bus
    4. Take the bus from Terminal de Autobuses de Querétaro Acceso 1 to Houstonbus bus
    5. Take the bus from Houston Bus Station to Panama City Beach Bus Stationbus bus
    2d 10h
    $383–588

  9. Bus #2

    1. Take the bus from Antigua Guatemala to San Cristóbal de las Casasbus bus
    2. Take the bus from San Cristóbal de las Casas to Coatzacoalcosbus bus
    3. Take the bus from Coatzacoalcos to Reynosabus bus
    4. Take the bus from McAllen Central Station to Houston - Harrisburg Blvdbus bus
    5. Take the bus from Houston Bus Station to Panama City Beach Bus Stationbus bus
    2d 10h
    $396–619

  10. Bus #3

    1. Take the bus from Antigua Guatemala to San Cristóbal de las Casasbus bus
    2. Take the bus from San Cristóbal de las Casas to Villahermosabus bus 4 / ...
    3. Take the bus from Villahermosa to Reynosabus bus
    4. Take the bus from McAllen Central Station to Houston - Harrisburg Blvdbus bus
    5. Take the bus from Houston Bus Station to Panama City Beach Bus Stationbus bus
    2d 11h
    $416–639

La Aurora International Airport (GUA) to Northwest Florida Beaches International Airport (ECP) flights

Calendar28Weekly Planes
Duration7h 53mAverage Duration
Ticket$128Cheapest Price
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Questions & Answers

Map of how to get from Antigua Guatemala to Panama City Beach.ExpandLaunch map view
  • Distance: 1,174 mi
  • Duration: 10h 40m

What companies run services between Antigua Guatemala and Panama City Beach, FL, USA?

United Airlines, Delta, and American Airlines fly from La Aurora International Airport (GUA) to Northwest Florida Beaches International Airport (ECP) 4 times a day. Alternatively, you can take a bus from Antigua Guatemala to Panama City Beach via Panajachel, San Cristóbal de las Casas, San Cristóbal de las Casas, Coatzacoalcos, Reynosa, Hidalgo International Bridge, Houston Bus Station, and Panama City Beach Bus Station in around 2d 9h.

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