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How to get fromAntigua Guatemala to Santa Anaby plane, bus, car, train, or shuttle

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There are 12 ways to get from Antigua Guatemala to Santa Ana by plane, bus, car, train, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly La Aurora International Airport to John Wayne Airport Orange County

    best
    1. Fly from La Aurora International Airport (GUA) to John Wayne Airport Orange County (SNA)plane plane GUA - SNA
    12h 13m
    $271–947

  2. Fly La Aurora International Airport to Los Angeles International Airport, train

    cheapest
    1. Fly from La Aurora International Airport (GUA) to Los Angeles International Airport (LAX)plane plane GUA - LAX
    2. Take the train from Los Angeles to Santa Anatrain train
    11h 23m
    $180–528

  3. Bus via Tepic

    1. Take the bus from Antigua Guatemala to San Cristóbal de las Casasbus bus
    2. Take the bus from San Cristóbal de las Casas to Pueblabus bus
    3. Take the bus from ACN Puebla to Tepicbus bus
    4. Take the bus from Tepic to Santa Anabus bus
    2d 12h
    $232–397

  4. Drive 2,599.7 mi

    1. Drive from Antigua Guatemala to Santa Anacar car 2,599.7 mi
    2d 2h
    $505–729

  5. Shuttle to Tapachula International Airport, fly to Tijuana International Airport, train

    1. Take a shuttle bus from Antigua Guatemala to Tapachulashuttle bus
    2. Fly from Tapachula International Airport (TAP) to Tijuana International Airport (TIJ)plane plane TAP - TIJ
    3. Take the train from San Diego to Santa Anatrain train
    13h 22m
    $249–713

  6. Fly La Aurora International Airport to San Diego International Airport, train

    1. Fly from La Aurora International Airport (GUA) to San Diego International Airport (SAN)plane plane GUA - SAN
    2. Take the train from San Diego to Santa Anatrain train
    14h 31m
    $233–832

  7. Fly La Aurora International Airport to Ontario International Airport, train

    1. Fly from La Aurora International Airport (GUA) to Ontario International Airport (ONT)plane plane GUA - ONT
    2. Take the train from San Bernardino Depot to Santa Anatrain train
    15h 11m
    $203–729

  8. Shuttle to Cuscatlán International Airport, fly to Los Angeles International Airport, train

    1. Take a shuttle bus from Antigua Guatemala to San Salvadorshuttle bus
    2. Fly from Cuscatlán International Airport (SAL) to Los Angeles International Airport (LAX)plane plane SAL - LAX
    3. Take the train from Los Angeles to Santa Anatrain train
    15h 44m
    $548–1,106

  9. Fly La Aurora International Airport to Tijuana International Airport, train

    1. Fly from La Aurora International Airport (GUA) to Tijuana International Airport (TIJ)plane plane GUA - TIJ
    2. Take the train from San Diego to Santa Anatrain train
    16h 10m
    $234–450

  10. Bus, train via San Antonio

    1. Take the bus from Antigua Guatemala to Comitánbus bus
    2. Take the bus from Comitán to Politécnicobus bus
    3. Take the bus from Terminal Central de Autobuses del Norte to San Antoniobus bus
    4. Take the train from San Antonio Station to Los Angelestrain train
    5. Take the train from Los Angeles to Santa Anatrain train
    3d
    $703–1,332

  11. Bus

    1. Take the bus from Antigua Guatemala to Tapachulabus bus
    2. Take the bus from Tapachula to Huixtlabus bus
    3. Take the bus from Huixtla to Tijuana Los Pinosbus bus
    4. Take the bus from Cross Border Xpress to Santa Anabus bus 2 / ...
    3d 14h
    $217–320

  12. Bus, train

    1. Take the bus from Guatemala City to Los Angelesbus bus
    2. Take the train from Los Angeles to Santa Anatrain train Pacific Surfliner
    3d 17h
    $303–426

La Aurora International Airport (GUA) to John Wayne Airport Orange County (SNA) flights

Calendar39Weekly Planes
Duration9h 27mAverage Duration
Ticket$231Cheapest Price
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Questions & Answers

Map of how to get from Antigua Guatemala to Santa Ana.ExpandLaunch map view
  • Distance: 2,188.7 mi
  • Duration: 12h 13m

What companies run services between Antigua Guatemala and Santa Ana, CA, USA?

American Airlines, United Airlines, and two other airlines fly from La Aurora International Airport (GUA) to John Wayne Airport Orange County (SNA) every 4 hours. Alternatively, you can take a bus from Antigua Guatemala to Santa Ana via San Cristóbal de las Casas, San Cristóbal de las Casas, Puebla, ACN Puebla, Tepic, and Tepic in around 2d 12h.

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