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How to get fromAntioch to Louisvilleby train, plane, bus, or car

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There are 9 ways to get from Antioch to Louisville by train, plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Chicago O'Hare International Airport, fly to Louisville International Airport

    best
    1. Take the train from Antioch to O'Hare Transfertrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF)plane plane ORD - SDF
    4h 57m
    $71–430

  2. Train, bus via Chicago

    cheapest
    1. Take the train from Antioch to Chicago Union Stationtrain train Ncs
    2. Take the bus from Chicago Bus Station to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    9h 18m
    $56–108

  3. Train, bus

    1. Take the train from Antioch to Chicago Union Stationtrain train Ncs
    2. Take the train from Chicago Union Station to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    10h 58m
    $89–183

  4. Drive 344.4 mi

    1. Drive from Antioch to Louisvillecar car 344.4 mi
    6h 16m
    $63–91

  5. Train to Chicago O'Hare International Airport, fly to Blue Grass Airport, drive

    1. Take the train from Antioch to O'Hare Transfertrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Blue Grass Airport (LEX)plane plane ORD - LEX
    3. Drive from Lexington-Airport-LEX to Louisvillecar car
    5h 6m
    $118–676

  6. Train to Chicago Midway International Airport, fly to Louisville International Airport

    1. Take the train from Antioch to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Louisville International Airport (SDF)plane plane MDW - SDF
    6h 1m
    $90–566

  7. Train to Chicago O'Hare International Airport, fly to Evansville, bus

    1. Take the train from Antioch to O'Hare Transfertrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Evansville (EVV)plane plane ORD - EVV
    3. Take the bus from Evansville, IN to Louisville, KYbus bus
    7h 5m
    $105–377

  8. Train to Chicago O'Hare International Airport, fly to Covington, bus

    1. Take the train from Antioch to O'Hare Transfertrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Covington (CVG)plane plane ORD - CVG
    3. Take the bus from Cincinnati - Downtown to Louisville, KY Bus Stationbus bus
    7h 29m
    $166–904

  9. Train, bus #2

    1. Take the train from Antioch to Chicago Union Stationtrain train Ncs
    2. Take the bus from Chicago Union Station to Louisville, KYbus bus Chicago
    9h 39m
    $57–68

Antioch to Louisville by train, foot, and bus

Calendar14Weekly Services
Duration9h 18mAverage Duration
Ticket$56Cheapest Price
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Questions & Answers

Map of how to get from Antioch to Louisville.ExpandLaunch map view
  • Distance: 330.8 mi
  • Duration: 4h 57m

What companies run services between Antioch, IL, USA and Louisville, KY, USA?

There is no direct connection from Antioch to Louisville. However, you can take the train to O'Hare Transfer, take the train to Terminal 2, walk to Chicago O'Hare International Airport (ORD) airport, fly to Louisville International Airport (SDF), walk to Louisville International Airport, then take the line 02 bus to 2nd @ York. Alternatively, you can take a train from Antioch to Louisville, KY via Chicago Union Station, Chicago Bus Station, and Indianapolis Union Station in around 9h 18m.

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