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How to get fromAntioch to St. Louisby train, plane, train (Amtrak), bus, or car

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There are 6 ways to get from Antioch to St. Louis by train, plane, train (Amtrak), bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Chicago O'Hare International Airport, fly

    best
    1. Take the train from Antioch to O'Hare Transfertrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane plane ORD - STL
    4h 13m
    $278–710

  2. Drive 324 mi

    cheapest
    1. Drive from Antioch to St. Louiscar car 324 mi
    5h 54m
    $60–86

  3. Train

    1. Take the train from Antioch to Chicago Union Stationtrain train Ncs
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    7h 25m
    $97–198

  4. Train, bus

    1. Take the train from Antioch to O'Hare Transfertrain train Ncs
    2. Take the bus from O'Hare Multi-Modal Facility to Illinois Terminalbus bus
    3. Take the bus from Champaign Intermodal Trans Ctr to St Louis Bus Stationbus bus
    10h 4m
    $79–117

  5. Train to Chicago Midway International Airport, fly

    1. Take the train from Antioch to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane plane MDW - STL
    5h 32m
    $87–566

  6. Train, bus to General Mitchell International Airport, fly

    1. Take the train from Antioch to O'Hare Transfertrain train
    2. Take the bus from Multi-Modal/Rental Car Facility to Mitchell Airportbus bus
    3. Fly from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL)plane plane MKE - STL
    6h 2m
    $523–898

Antioch to St. Louis by train

Calendar35Weekly Trains
Duration7h 25mAverage Duration
Ticket$97Cheapest Price
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Questions & Answers

Map of how to get from Antioch to St. Louis.ExpandLaunch map view
  • Distance: 311.2 mi
  • Duration: 4h 13m

What companies run services between Antioch, IL, USA and St. Louis, MO, USA?

You can take a train from Antioch to St. Louis via Chicago Union Station in around 7h 25m.

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Bus operators

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