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How to get fromAntofagasta to Cuscoby plane, bus, or car

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There are 5 ways to get from Antofagasta to Cusco by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Antofagasta Airport (ANF) to Alejandro Velasco Astete International Airport (CUZ)plane plane ANF - CUZ
    5h 52m
    $194–428

  2. Bus #2

    cheapest
    1. Take the bus from Terminal de Buses Cardenal Carlos Oviedo Cavada to Terminal Rodoviario de Aricabus bus
    2. Take the bus from Terminal Internacional to Tacnabus bus
    3. Take the bus from Tacna Bus Station to Cusco Bus Stationbus bus
    28h 39m
    $47–111

  3. Bus via Moquegua

    1. Take the bus from Terminal de Buses Cardenal Carlos Oviedo Cavada to Terminal Rodoviario de Aricabus bus
    2. Take the bus from Terminal Internacional to Tacnabus bus
    3. Take the bus from Tacna to Moqueguabus bus
    4. Take the bus from Moquegua to Arequipabus bus
    5. Take the bus from Arequipa to Cuscobus bus
    22h 16m

  4. Drive 1,555.4 km

    1. Drive from Antofagasta to Cuscocar car 1,555.4 km
    22h 22m
    $234–338

  5. Bus

    1. Take the bus from Terminal de Buses Cardenal Carlos Oviedo Cavada to Terminal Rodoviario de Aricabus bus
    2. Take the bus from Terminal Internacional to Tacnabus bus
    3. Take the bus from Tacna to Arequipabus bus
    4. Take the bus from Arequipa to Cuscobus bus
    27h
    $70–157

Antofagasta to Cusco by bus

Calendar7Weekly Buses
Duration27hAverage Duration
Ticket$70Cheapest Price
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Questions & Answers

Map of how to get from Antofagasta to Cusco.ExpandLaunch map view
  • Distance: 1,139 km
  • Duration: 5h 52m

What companies run services between Antofagasta, Chile and Cusco, Peru?

LATAM Chile flies from Antofagasta Airport (ANF) to Alejandro Velasco Astete International Airport (CUZ) once daily. Alternatively, you can take a bus from Terminal de Buses Cardenal Carlos Oviedo Cavada to Cusco via Terminal Rodoviario de Arica, Terminal Internacional, Tacna, Moquegua, and Arequipa in around 22h 16m.

Airlines
Bus operators

Want to know more about travelling around the world?

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