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How to get fromAntofagasta to Santa Cruzby plane, bus, car, or bus (Flixbus)

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There are 5 ways to get from Antofagasta to Santa Cruz by plane, bus, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly, bus

    best
    1. Fly from Antofagasta Airport (ANF) to Comodoro Arturo Merino Benítez International Airport (SCL)plane plane ANF - SCL
    2. Take the bus from Terminal Sur de Santiago to Santa Cruzbus bus
    6h
    $71–246

  2. Bus

    cheapest
    1. Take the bus from Terminal de Buses Cardenal Carlos Oviedo Cavada to Terminal San Borjabus bus Santiago / ...
    2. Take the bus from Terminal Sur de Santiago to Terminal de Buses Santa Cruzbus bus Santiago
    21h 54m
    $33–114

  3. Drive 1,466.3 km

    1. Drive from Antofagasta to Santa Cruzcar car 1,466.3 km
    18h 17m
    $181–262

  4. Bus via Santiago

    1. Take the bus from Antofagasta to Santiagobus bus FlixBus CL071 / ...
    2. Take the bus from Terminal Sur de Santiago to Terminal de Buses Santa Cruzbus bus Santiago
    22h 32m
    $134–244

  5. Bus #2

    1. Take the bus from Terminal de Buses Cardenal Carlos Oviedo Cavada to Terminal Alameda - Turbusbus bus Santiago / ...
    2. Take the bus from Terminal Sur de Santiago to Santa Cruzbus bus FlixBus CL027
    25h 10m
    $41–116

Antofagasta Airport (ANF) to Comodoro Arturo Merino Benítez International Airport (SCL) flights

Calendar123Weekly Planes
Duration1h 54mAverage Duration
Ticket$34Cheapest Price
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Questions & Answers

Map of how to get from Antofagasta to Santa Cruz.ExpandLaunch map view
  • Distance: 1,345.6 km
  • Duration: 6h

What companies run services between Antofagasta, Chile and Santa Cruz, O'Higgins, Chile?

You can take a bus from Jose Santos Ossa esq. General Baquedano to Terminal de Buses Santa Cruz via Victor Jara esq. Ollague, Terminal de Buses Cardenal Carlos Oviedo Cavada, Terminal San Borja, and Terminal Sur de Santiago in around 21h 54m.

Airlines
Bus operators

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