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How to get fromAntofagasta to Santa Cruz de la Sierraby plane, bus, or car

Find Transport to Santa Cruz de la Sierra

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There are 3 ways to get from Antofagasta to Santa Cruz de la Sierra by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Antofagasta Airport (ANF) to Viru Viru International Airport (VVI)plane plane ANF - VVI
    8h 8m
    $255–579
  2. Bus

    cheapest
    1. Take the bus from Terminal de Buses Cardenal Carlos Oviedo Cavada to Santa Cruzbus bus Santa Cruz
    21h 45m
    $40
  3. Drive 1,432.6 km

    1. Drive from Antofagasta to Santa Cruz de la Sierracar car 1,432.6 km
    20h 47m
    $177–256

Antofagasta Airport (ANF) to Viru Viru International Airport (VVI) flights

Calendar3Weekly Planes
Duration7h 31mAverage Duration
Ticket$215Cheapest Price
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Questions & Answers

What companies run services between Antofagasta, Chile and Santa Cruz de la Sierra, Bolivia?

LATAM Chile and Boliviana de Aviación fly from Antofagasta Airport (ANF) to Viru Viru International Airport (VVI) 3 times a week. Alternatively, Jet Nort Super Class operates a bus from Terminal de Buses Cardenal Carlos Oviedo Cavada to Santa Cruz 4 times a week. Tickets cost $40 and the journey takes 21h 45m.

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