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How to get fromApopka to Florida Keysby plane, bus, taxi, train, car, shuttle, bus (Flixbus, Greyhound), or bus (Greyhound)

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There are 9 ways to get from Apopka to Florida Keys by plane, bus, taxi, train, car, shuttle, bus (Flixbus, Greyhound), or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Orlando Sanford to Key West International Airport, bus

    best
    1. Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane plane SFB - EYW
    2. Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodgebus bus
    4h 42m
    $173–416

  2. Bus

    cheapest
    1. Take the bus from Orlando to Miami Airport Stationbus bus FlixBus 2411 / ...
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus Greyhound US0720s
    13h 10m
    $53–96

  3. Taxi, train, bus

    1. Take the taxi from Apopka to Orlandotaxi taxi
    2. Take the train from Orlando to Miamitrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    10h 55m
    $137–298

  4. Train, bus

    1. Take the train from Winter Park Amtrak Station to Hollywood Amtrak Stationtrain train Silver Meteor / ...
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus Greyhound US0720s
    14h 59m
    $91–197

  5. Drive  368.6 mi

    1. Drive from Apopka to Florida Keyscar car 368.6 mi
    7h 36m
    $68–98

  6. Line 106 bus to Orlando, fly to Key West International Airport, bus

    1. Take the bus from E Main St & S Forest Ave to N Garland Ave & W Amelia Stbus bus
    2. Fly from Orlando (MCO) to Key West International Airport (EYW)plane plane MCO - EYW
    3. Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodgebus bus
    6h 59m
    $146–748

  7. Fly Orlando to Miami International Airport, shuttle

    1. Fly from Orlando (MCO) to Miami International Airport (MIA)plane plane MCO - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    9h 23m
    $756–1,288

  8. Bus, shuttle

    1. Take the bus from Orlando - RedCoach Station, FL to Miami Airportbus bus Tallahassee
    2. Take a shuttle bus from Miami, FL - International Airport to Summerland Key - Mote Marine Labshuttle bus To the Keys
    12h 50m
    $209–266

  9. Bus via Pembroke Pines

    1. Take the bus from Orlando to Sheridan Tri-Rail Stationbus bus Orlando to Miami
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus Greyhound US0720s
    13h 38m
    $56–92

Apopka to Florida Keys by bus, train, and foot

Calendar14Weekly Services
Duration14h 59mAverage Duration
Ticket$91Cheapest Price
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Comparing Your Travel Options

Map of how to get from Apopka to Florida Keys.ExpandLaunch map view
  • Distance: 335.7 mi
  • Duration: 4h 42m

What companies run services between Apopka, FL, USA and Florida Keys, FL, USA?

You can take a bus from E Main St & S Forest Ave to Florida Keys via N Garland Ave & W Amelia St, Florida Mall, Orlando, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 13h 10m.

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