There are 8 ways to get from Apopka to Key West by plane, taxi, train, bus, car, shuttle, bus (Flixbus, Greyhound), or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Orlando Sanford
best- Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane SFB - EYW
1h 55m$107–355Bus
cheapest- Take the bus from Orlando to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
13h 57m$54–91Taxi, train, bus
- Take the taxi from Apopka to Orlandotaxi
- Take the train from Orlando to Miamitrain
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
11h 43m$138–298Train, bus
- Take the train from Winter Park Amtrak Station to Hollywood Amtrak Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
15h 46m$87–197Drive 384 mi
- Drive from Apopka to Key Westcar 384 mi
7h 59m$71–102Line 106 bus to Orlando, fly
- Take the bus from E Main St & S Forest Ave to N Garland Ave & W Amelia Stbus
- Fly from Orlando (MCO) to Key West International Airport (EYW)plane MCO - EYW
4h 13m$80–717Bus, shuttle
- Take the bus from Orlando - RedCoach Station, FL to Miami Airportbus Tallahassee
- Take a shuttle bus from Miami, FL - International Airport to Key West, FLTo the Keys
13h 14m$229–286Bus via Pembroke Pines
- Take the bus from Orlando to Sheridan Tri-Rail Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
14h 24m$57–92
Apopka to Key West by bus, train, and foot
Comparing Your Travel Options
The cheapest way to get from Apopka to Key West is to bus which costs $50 - $95 and takes 13h 57m.
The fastest way to get from Apopka to Key West is to fly which takes 1h 55m and costs $100 - $360.
No, there is no direct bus from Apopka to Key West. However, there are services departing from E Main St & S Forest Ave and arriving at N Roosevelt & 3rd Street via N Garland Ave & W Amelia St, Orlando, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 13h 57m.
The distance between Apopka and Key West is 318 miles. The road distance is 386.2 miles.
The best way to get from Apopka to Key West without a car is to taxi and train and bus which takes 11h 43m and costs $130 - $300.
It takes approximately 1h 55m to get from Apopka to Key West, including transfers.
Apopka to Key West bus services, operated by Flixbus USA, depart from Orlando station.
The best way to get from Apopka to Key West is to fly which takes 1h 55m and costs $100 - $360. Alternatively, you can bus, which costs $50 - $95 and takes 13h 57m.
Apopka to Key West bus services, operated by Flixbus USA, arrive at Miami Airport Station.
Yes, the driving distance between Apopka to Key West is 386 miles. It takes approximately 7h 59m to drive from Apopka to Key West.
What companies run services between Apopka, FL, USA and Key West, FL, USA?
Allegiant Air flies from Orlando Sanford (SFB) to Key West International Airport (EYW) 4 times a week. Alternatively, you can take a bus from E Main St & S Forest Ave to N Roosevelt & 3rd Street via N Garland Ave & W Amelia St, Florida Mall, Orlando, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 13h 57m.
- Website
- allegiantair.com
Flights from Orlando Sanford to Key West International Airport
- Ave. Duration
- 1h 14m
- When
- Friday, Sunday, Thursday, and Monday
- Estimated price
- $35–270
- Phone
- +1 831-539-2901
- [email protected]
- Website
- gobrightline.com
Train from Orlando to Miami
- Ave. Duration
- 3h 36m
- Frequency
- Every 2 hours
- Estimated price
- $40–170
- Book at
- Brightline
- Smart
- $40–90
- Premium
- $110–170
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $20–35
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $20–35
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $20–35
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $20–35
- Website
- Greyhound
- Ave. Duration
- 42 min
- Estimated price
- $70–90
Diamond Cab Company
- Phone
- +1 407-523-3333
- Website
- diamondcabco.com
Orlando Cab Co.
- Phone
- +1 407-575-7757
- Website
- myorlandocab.com
Yellow Meter Taxicab
- Phone
- (407) 422-2222
- Website
- yellowmetertaxicab.com
24Seven Taxi
- Phone
- (321) 247 8294
- Website
- 24seven-taxi.com
Orlando Taxi 24
- Phone
- (407) 529-4848
Quick Cab
- Phone
- (407) 447-1444
Want to know more about travelling around United States
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Booking & Getting There
There are 967+ hotels available in Key West.




