There are 4 ways to get from Apopka to Sanibel Island by bus, plane, bus (Flixbus), car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Line 106 bus, fly
best- Take the bus from E Main St & S Forest Ave to N Garland Ave & W Amelia Stbus
- Fly from Orlando (MCO) to Ft. Myers (RSW)plane MCO - RSW
4h 20m$369–694Drive 179.1 mi
cheapest- Drive from Apopka to Sanibel Islandcar 179.1 mi
3h 46m$33–48Bus (Flixbus)
- Take the bus from Orlando Bus Station to Fort Myers Bus Stopbus FlixBus 2421
8h 4m$87–132Train, bus
- Take the train from Orlando to Tampatrain Floridian
- Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus FlixBus 2421
9h 36m$111–174
Orlando (MCO) to Ft. Myers (RSW) flights
Questions & Answers
The cheapest way to get from Apopka to Sanibel Island is to drive which costs $30 - $50 and takes 3h 46m.
The fastest way to get from Apopka to Sanibel Island is to drive which takes 3h 46m and costs $30 - $50.
No, there is no direct bus from Apopka to Sanibel Island. However, there are services departing from E Main St & S Forest Ave and arriving at Fort Myers Bus Stop via N Garland Ave & W Amelia St and Orlando Bus Station. The journey, including transfers, takes approximately 8h 4m.
The distance between Apopka and Sanibel Island is 186 miles. The road distance is 180.1 miles.
The best way to get from Apopka to Sanibel Island without a car is to bus which takes 8h 4m and costs $85 - $140.
It takes approximately 4h 20m to get from Apopka to Sanibel Island, including transfers.
Apopka to Sanibel Island bus services, operated by Flixbus USA, depart from Orlando Bus Station.
Apopka to Sanibel Island bus services, operated by Flixbus USA, arrive at Fort Myers Bus Stop station.
Yes, the driving distance between Apopka to Sanibel Island is 180 miles. It takes approximately 3h 46m to drive from Apopka to Sanibel Island.
There are 3519+ hotels available in Sanibel Island.
What companies run services between Apopka, FL, USA and Sanibel Island, FL, USA?
Flixbus USA operates a bus from Orlando Bus Station to Fort Myers Bus Stop every 4 hours. Tickets cost $30–60 and the journey takes 5h 10m.
- Website
- southwest.com
Flights from Orlando to Ft. Myers
- Ave. Duration
- 1h 2m
- When
- Every day
- Estimated price
- $35–270
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Orlando to Tampa
- Ave. Duration
- 2h 8m
- Frequency
- Once daily
- Estimated price
- $28–60
- Website
- Amtrak
- Phone
- +1 407-841-5969
- [email protected]
- Website
- Lynx
Bus from E Main St & S Forest Ave to N Garland Ave & W Amelia St
- Ave. Duration
- 45 min
- Frequency
- Hourly
- Estimated price
- $2
- Website
- Lynx
- Schedules at
- Lynx Routes and Schedules
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Orlando Bus Station to Fort Myers Bus Stop
- Ave. Duration
- 5h 10m
- Frequency
- Every 4 hours
- Estimated price
- $30–60
- Schedules at
- Flixbus USA
Bus from Tampa Bus Station to Fort Myers Bus Stop
- Ave. Duration
- 3h 5m
- Frequency
- Every 4 hours
- Estimated price
- $21–35
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide







