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How to get fromAppleton to Charlestonby plane, bus, train, bus (Flixbus, Greyhound), or car

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There are 6 ways to get from Appleton to Charleston by plane, bus, train, bus (Flixbus, Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Appleton International Airport to Charleston International Airport

    best
    1. Fly from Appleton International Airport (ATW) to Charleston International Airport (CHS)plane plane ATW - CHS
    6h 20m
    $116–519

  2. Bus, train

    1. Take the bus from Appleton to Milwaukeebus bus
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain train
    4. Take the train from Petersburg Amtrak Station to Charleston Amtrak Stationtrain train
    34h 43m
    $402–883

  3. Bus

    1. Take the bus from Appleton Transit Center to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Charleston Bus Stationbus bus
    35h 42m
    $196–377

  4. Drive  1,061.8 mi

    1. Drive from Appleton to Charlestoncar car 1,061.8 mi
    19h 23m
    $194–280

  5. Fly Green Bay to Charleston International Airport

    1. Fly from Green Bay (GRB) to Charleston International Airport (CHS)plane plane GRB - CHS
    7h 31m
    $138–544

  6. Fly Appleton International Airport to Hilton Head Airport, drive

    1. Fly from Appleton International Airport (ATW) to Hilton Head Airport (HHH)plane plane ATW - HHH
    2. Drive from Hilton Head Airport (HHH) to Charlestoncar car
    7h 27m
    $122–494

Appleton to Charleston by bus

Calendar5Weekly Buses
Duration35h 42mAverage Duration
Ticket$196Cheapest Price
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Questions & Answers

Map of how to get from Appleton to Charleston.ExpandLaunch map view
  • Distance: 927.5 mi
  • Duration: 6h 20m

What companies run services between Appleton, WI, USA and Charleston, SC, USA?

United Airlines, Delta, and American Airlines fly from Appleton International Airport (ATW) to Charleston International Airport (CHS) every 3 hours. Alternatively, you can take a bus from Appleton Transit Center to Transit Mall via Chicago Bus Station, Atlanta Bus Station, Charleston Bus Station, North Charleston Transit Center, N. Charleston SuperStop, and Rivers Ave / Cosgrove Ave in around 35h 42m.

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