There are 7 ways to get from Appleton to Columbia by plane, bus, train, taxi, car, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Appleton International Airport
best- Fly from Appleton International Airport (ATW) to Columbia Regional Airport (COU)plane ATW - COU
4h 21m$119–442Drive 499.3 mi
cheapest- Drive from Appleton to Columbiacar 499.3 mi
9h 53m$92–132Bus, train, taxi
- Take the bus from Appleton to Milwaukeebus
- Take the train from Milwaukee to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Jefferson City Stationtrain
- Take the taxi from Jefferson City Station to Columbiataxi
14h 24m$257–453Bus, train
- Take the bus from Appleton Transit Center to Chicago Bus Stationbus
- Take the train from Chicago Union Station to St. Louistrain
- Take the bus from St Louis Bus Station to Columbiabus
14h 25m$121–249Fly from Green Bay
- Fly from Green Bay (GRB) to Columbia Regional Airport (COU)plane GRB - COU
5h 39m$146–467Bus, train via Milwaukee
- Take the bus from Appleton to Milwaukeebus
- Take the train from Milwaukee to Chicago Union Stationtrain
- Take the train from Chicago Union Station to St. Louistrain
- Take the bus from St Louis Bus Station to Columbiabus
14h 50m$129–278Bus
- Take the bus from Appleton Transit Center to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Columbiabus
15h 25m$96–154
Appleton to Columbia by bus, foot, and train
Comparing Your Travel Options
The cheapest way to get from Appleton to Columbia is to drive which costs $90 - $140 and takes 9h 53m.
The fastest way to get from Appleton to Columbia is to fly which takes 4h 21m and costs $110 - $450.
No, there is no direct bus from Appleton to Columbia. However, there are services departing from Appleton Transit Center and arriving at Columbia via Chicago Bus Station and St Louis Bus Station. The journey, including transfers, takes approximately 15h 25m.
The distance between Appleton and Columbia is 443 miles. The road distance is 502.2 miles.
The best way to get from Appleton to Columbia without a car is to bus and train and taxi which takes 14h 24m and costs $250 - $460.
It takes approximately 4h 21m to get from Appleton to Columbia, including transfers.
Appleton to Columbia bus services, operated by Flixbus USA, depart from Appleton Transit Center station.
The best way to get from Appleton to Columbia is to fly which takes 4h 21m and costs $110 - $450. Alternatively, you can bus, which costs $95 - $160 and takes 15h 25m.
Appleton to Columbia bus services, operated by Flixbus USA, arrive at Chicago Bus Station.
Yes, the driving distance between Appleton to Columbia is 502 miles. It takes approximately 9h 53m to drive from Appleton to Columbia.
What companies run services between Appleton, WI, USA and Columbia, MO, USA?
United Airlines, American Airlines, and Allegiant Air fly from Appleton International Airport (ATW) to Columbia Regional Airport (COU) every 4 hours. Alternatively, you can take a bus from Appleton Transit Center to Columbia via Chicago Bus Station and St Louis Bus Station in around 15h 25m.
- Website
- united.com
Flights from Appleton International Airport to Columbia Regional Airport via Chicago O'Hare
- Ave. Duration
- 6h 1m
- When
- Every day
- Estimated price
- $55–360
Flights from Green Bay to Columbia Regional Airport via Chicago O'Hare
- Ave. Duration
- 4h 59m
- When
- Every day
- Estimated price
- $60–360
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $21–50
- Website
- Amtrak
Train from Chicago Union Station to Jefferson City Station
- Ave. Duration
- 7h 46m
- Frequency
- Once daily
- Estimated price
- $100–230
- Website
- Amtrak
Train from Chicago Union Station to St. Louis
- Ave. Duration
- 4h 46m
- Frequency
- 5 times a day
- Estimated price
- $70–170
- Website
- Amtrak
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $21–50
- Website
- Amtrak
Train from Chicago Union Station to St. Louis
- Ave. Duration
- 4h 46m
- Frequency
- 5 times a day
- Estimated price
- $70–170
- Website
- Amtrak
- Phone
- 920 496 3600
- Website
- golamers.com
Bus from Appleton to Milwaukee
- Ave. Duration
- 2h 35m
- Frequency
- Twice daily
- Estimated price
- $23–27
- Schedules at
- golamers.com
Bus from Appleton to Milwaukee
- Ave. Duration
- 2h 35m
- Frequency
- Twice daily
- Estimated price
- $23–27
- Schedules at
- golamers.com
Want to know more about travelling around United States
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Booking & Getting There
Book your Appleton to Columbia bus tickets online with Omio and FlixBus.
There are 59+ hotels available in Columbia.





