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How to get fromAppleton to Greenvilleby plane, bus (Flixbus, Greyhound), bus, train, car, or taxi

Find Transport to Greenville

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There are 7 ways to get from Appleton to Greenville by plane, bus (Flixbus, Greyhound), bus, train, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Appleton International Airport to Greenville–Spartanburg International Airport

    best
    1. Fly from Appleton International Airport (ATW) to Greenville–Spartanburg International Airport (GSP)plane plane ATW - GSP
    4h 57m
    $159–712

  2. Drive  857.1 mi

    cheapest
    1. Drive from Appleton to Greenvillecar car 857.1 mi
    16h 7m
    $157–226

  3. Bus

    1. Take the bus from Appleton Transit Center to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus
    27h 8m
    $180–298

  4. Bus, train via Cary

    1. Take the bus from Appleton to Milwaukeebus bus
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Carytrain train
    4. Take the train from Cary to Charlotte Amtrak Stationtrain train
    5. Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus bus
    38h 31m
    $375–885

  5. Fly Appleton International Airport to Asheville Regional Airport, taxi

    1. Fly from Appleton International Airport (ATW) to Asheville Regional Airport (AVL)plane plane ATW - AVL
    2. Take the taxi from Asheville-Airport-AVL to Greenvilletaxi taxi
    5h 53m
    $224–587

  6. Fly Green Bay to Greenville–Spartanburg International Airport

    1. Fly from Green Bay (GRB) to Greenville–Spartanburg International Airport (GSP)plane plane GRB - GSP
    6h 24m
    $181–737

  7. Bus, train

    1. Take the bus from Appleton to Milwaukeebus bus
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    3. Take the bus from Chicago Train Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus
    27h 16m
    $194–325

Appleton International Airport (ATW) to Greenville–Spartanburg International Airport (GSP) flights

Calendar55Weekly Planes
Duration6h 7mAverage Duration
Ticket$116Cheapest Price
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Comparing Your Travel Options

Map of how to get from Appleton to Greenville.ExpandLaunch map view
  • Distance: 745.5 mi
  • Duration: 4h 57m

What companies run services between Appleton, WI, USA and Greenville, SC, USA?

Delta, United Airlines, and American Airlines fly from Appleton International Airport (ATW) to Greenville–Spartanburg International Airport (GSP) every 4 hours. Alternatively, you can take a bus from Appleton Transit Center to Greenville via Chicago Bus Station, Atlanta Bus Station, Garnett Station, Lindbergh Center Station, Lindbergh Center Station - Bay D, Shallowford Rd @ New Peachtree, Atlanta, and Taqueria Guadalajara - Greenville in around 27h 8m.

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