There are 7 ways to get from Appleton to Indianapolis by plane, bus (Flixbus, Greyhound), bus, train, car, or bus (Flixbus, Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Appleton International Airport to Indianapolis
best- Fly from Appleton International Airport (ATW) to Indianapolis (IND)plane ATW - IND
4h 37m$86–489Bus
cheapest- Take the bus from Appleton Transit Center to Chicago Bus Stationbus FlixBus 2550
- Take the bus from Chicago Bus Station to Indianapolis Union Stationbus Greyhound US0100 / ...
8h 35m$57–88Bus, train
- Take the bus from Appleton to Milwaukeebus
- Take the train from Milwaukee to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Indianapolistrain
10h 58m$81–193Drive 368.5 mi
- Drive from Appleton to Indianapoliscar 368.5 mi
6h 36m$68–98Fly Green Bay to Indianapolis
- Fly from Green Bay (GRB) to Indianapolis (IND)plane GRB - IND
6h 10m$108–514Fly Appleton International Airport to Purdue University Airport, bus
- Fly from Appleton International Airport (ATW) to Purdue University Airport (LAF)plane ATW - LAF
- Take the bus from Lafayette Amtrak Station to Indianapolis Union Stationbus
6h 13m$74–383Bus via Lafayette
- Take the bus from Appleton Transit Center to Chicago Bus Stationbus
- Take the bus from Chicago Union Station to Lafayette Amtrak Stationbus
- Take the bus from Lafayette Amtrak Station to Indianapolis Union Stationbus
10h 19m$66–133
Appleton to Indianapolis by bus
Comparing Your Travel Options
The cheapest way to get from Appleton to Indianapolis is to bus which costs $55 - $90 and takes 8h 35m.
The fastest way to get from Appleton to Indianapolis is to fly which takes 4h 37m and costs $85 - $490.
No, there is no direct bus from Appleton to Indianapolis station. However, there are services departing from Appleton Transit Center and arriving at Indianapolis Union Station via Chicago Bus Station. The journey, including transfers, takes approximately 8h 35m.
The distance between Appleton and Indianapolis is 356 miles. The road distance is 370.7 miles.
The best way to get from Appleton to Indianapolis without a car is to bus which takes 8h 35m and costs $55 - $90.
It takes approximately 4h 37m to get from Appleton to Indianapolis, including transfers.
Appleton to Indianapolis bus services, operated by Flixbus USA, depart from Appleton Transit Center station.
The best way to get from Appleton to Indianapolis is to fly which takes 4h 37m and costs $85 - $490. Alternatively, you can bus, which costs $55 - $90 and takes 8h 35m.
Appleton to Indianapolis bus services, operated by Flixbus USA, arrive at Chicago Bus Station.
Indianapolis is 1h ahead of Appleton. It is currently 10:56 PM in Appleton and 11:56 PM in Indianapolis.
What companies run services between Appleton, WI, USA and Indianapolis, IN, USA?
United Airlines, Delta, and American Airlines fly from Appleton International Airport (ATW) to Indianapolis (IND) hourly. Alternatively, you can take a bus from Appleton Transit Center to Indianapolis Union Station via Chicago Bus Station in around 8h 35m.
- Website
- delta.com
Flights from Appleton International Airport to Indianapolis via Minneapolis
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $100–600
Flights from Appleton International Airport to Indianapolis via Detroit
- Ave. Duration
- 5h 14m
- When
- Every day
- Estimated price
- $85–550
Flights from Appleton International Airport to Indianapolis via Atlanta
- Ave. Duration
- 6h 17m
- When
- Every day
- Estimated price
- $140–700
Flights from Green Bay to Indianapolis via Minneapolis
- Ave. Duration
- 4h 38m
- When
- Every day
- Estimated price
- $100–600
Flights from Green Bay to Indianapolis via Detroit
- Ave. Duration
- 5h 33m
- When
- Every day
- Estimated price
- $85–550
Flights from Green Bay to Indianapolis via Atlanta
- Ave. Duration
- 6h 16m
- When
- Every day
- Estimated price
- $140–750
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $20–50
- Website
- Amtrak
Train from Chicago Union Station to Indianapolis
- Ave. Duration
- 4h 54m
- Frequency
- 3 times a week
- Estimated price
- $45–120
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Appleton Transit Center to Chicago Bus Station
- Ave. Duration
- 4h 30m
- Frequency
- 5 times a week
- Estimated price
- $29–45
- Schedules at
- Flixbus USA
Bus from Appleton to Milwaukee
- Ave. Duration
- 2h 10m
- Frequency
- 5 times a week
- Estimated price
- $15–24
- Schedules at
- Flixbus USA
Bus from Appleton Transit Center to Chicago Bus Station
- Ave. Duration
- 4h 30m
- Frequency
- 5 times a week
- Estimated price
- $29–45
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
Booking & Getting There
Yes, the driving distance between Appleton to Indianapolis is 371 miles. It takes approximately 6h 36m to drive from Appleton to Indianapolis.
Book your Appleton to Indianapolis bus tickets online with Omio and FlixBus.
There are 875+ hotels available in Indianapolis.





