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How to get fromAppleton to Louisvilleby plane, bus (Greyhound, Flixbus, Amtrak), bus, train, car, or taxi

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There are 8 ways to get from Appleton to Louisville by plane, bus (Greyhound, Flixbus, Amtrak), bus, train, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Appleton International Airport to Louisville International Airport

    best
    1. Fly from Appleton International Airport (ATW) to Louisville International Airport (SDF)plane plane ATW - SDF
    5h 1m
    $115–670

  2. Fly Appleton International Airport to Blue Grass Airport, drive

    cheapest
    1. Fly from Appleton International Airport (ATW) to Blue Grass Airport (LEX)plane plane ATW - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    5h 33m
    $87–396

  3. Bus via Indianapolis

    1. Take the bus from Oshkosh to Milwaukeebus bus
    2. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Indianapolis Union Stationbus bus
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    13h 1m
    $117–184

  4. Bus, train

    1. Take the bus from Oshkosh to Milwaukeebus bus
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Indianapolistrain train
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    13h 28m
    $235–370

  5. Drive  483.2 mi

    1. Drive from Appleton to Louisvillecar car 483.2 mi
    8h 28m
    $89–128

  6. Taxi to Green Bay, fly to Louisville International Airport

    1. Take the taxi from Appleton to Green Bay (GRB)taxi taxi
    2. Fly from Green Bay (GRB) to Louisville International Airport (SDF)plane plane GRB - SDF
    5h 53m
    $200–770

  7. Bus to General Mitchell International Airport, fly to Louisville International Airport

    1. Take the bus from Oshkosh to Milwaukeebus bus
    2. Fly from General Mitchell International Airport (MKE) to Louisville International Airport (SDF)plane plane MKE - SDF
    7h 57m
    $190–884

  8. Bus

    1. Take the bus from Oshkosh to Milwaukeebus bus
    2. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Union Station to Louisville, KYbus bus
    13h 55m
    $115–149

Appleton International Airport (ATW) to Louisville International Airport (SDF) flights

Calendar83Weekly Planes
Duration5h 18mAverage Duration
Ticket$104Cheapest Price
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Comparing Your Travel Options

Map of how to get from Appleton to Louisville.ExpandLaunch map view
  • Distance: 454.5 mi
  • Duration: 5h 1m

What companies run services between Appleton, WI, USA and Louisville, KY, USA?

Delta, American Airlines, and two other airlines fly from Appleton International Airport (ATW) to Louisville International Airport (SDF) every 2 hours. Alternatively, you can take a bus from Prospect and Walnut to Louisville, KY via Church @ Doty - Neenah Transit Center, Oshkosh, Milwaukee, Milwaukee Intermodal Station, Chicago Bus Station, and Indianapolis Union Station in around 13h 1m.

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